Xiaoshan Wang
Anhui University
4 Papers
20 Citations
Xiaoshan Wang is an academic researcher from Anhui University. The author has contributed to research in topics: Apoptosis & Biology. The author has an hindex of 4, co-authored 4 publications.
Chat about Author
Papers
Gambogenic acid inhibits proliferation of A549 cells through apoptosis-inducing and cell cycle arresting.
Qinglin Li,Hui Cheng,Guo-Qi Zhu,Li Yang,An Zhou,Xiaoshan Wang,Nianbai Fang,Lunzhu Xia,Jingjing Su,Mei Wang,Daiying Peng,Qi Xu +11 more
TL;DR: The results suggested that GNA significantly inhibited the proliferation of several tumor cell lines in vitro and in vivo and might suggest that G NA inhibits tumor cell proliferation via apoptosis-induction and cell cycle arrest.
82
Gambogenic acid induced mitochondrial-dependent apoptosis and referred to phospho-Erk1/2 and phospho-p38 MAPK in human hepatoma HepG2 cells.
Fenggen Yan,Mei Wang,Jiaming Li,Hui Cheng,Jingjing Su,Xiaoshan Wang,Haiyun Wu,Lunzhu Xia,Xiaoxiang Li,Hebron C. Chang,Qinglin Li +10 more
TL;DR: Results indicated that gambogenic acid induced mitochondrial oxidative stress and activated caspases through a caspase-3 and casp enzyme-9-dependent apoptosis pathway and was involved in the phospho-Erk1/2 and phospho -p38 MAPK proteins expression changes in HepG2 cells.
70
Gambogenic acid mediated apoptosis through the mitochondrial oxidative stress and inactivation of Akt signaling pathway in human nasopharyngeal carcinoma CNE-1 cells.
TL;DR: The results indicated that Gambogenic acid mediated apoptosis through inactivation of Akt, accompanied with mitochondrial oxidative stress and cross-talk with Bcl-2 family in the process of apoptosis.
62
Gambogenic acid inhibits proliferation of A549 cells through apoptosis inducing through up-regulation of the p38 MAPK cascade.
Hui Cheng,Jingjing Su,Jian-Ya Peng,Mei Wang,Xun-Cui Wang,Fenggen Yan,Xiaoshan Wang,Qinglin Li +7 more
TL;DR: This paper investigated whether GNA-induced apoptosis is critically mediated by the p38 mitogen-activated protein kinase (MAPK) pathway and suggested that up-regulation of the p 38 MAPK cascade may account for the activation of GNA's induced apoptosis.
21