Xiaoping Zhou
Second Military Medical University
8 Papers
7 Citations
Xiaoping Zhou is an academic researcher from Second Military Medical University. The author has contributed to research in topics: Glioma & Leptin receptor. The author has an hindex of 6, co-authored 8 publications.
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Papers
High expression of leptin receptor leads to temozolomide resistance with exhibiting stem/progenitor cell features in gliobalastoma.
Guosheng Han,Lai-xing Wang,Wen-Yuan Zhao,Yue Zhijian,Zhao Rui,Li Yanan,Xiaoping Zhou,xiaohu hu,Liu Jianmin +8 more
TL;DR: In this study, it is found that leptin receptor-positive glioblastoma cells were resistant to temozolomide (TMZ), and TMZ-resistant cells exhibited high expression of ObR, which explained the reason for TMZ resistance of obR+ cells.
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Leptin enhances the invasive ability of glioma stem-like cells depending on leptin receptor expression.
Guosheng Han,Wen-Yuan Zhao,Laixing Wang,Yue Zhijian,Rui Zhao,Li Yanan,Xiaoping Zhou,Xiaowu Hu,Jianmin Liu +8 more
TL;DR: The results indicated that leptin served as a key intermediary linking the accumulation of excess adipokine to the invasion of glioma stem-like cells, which may be a novel therapeutic target for suppressing tumor invasion and recurrence.
15
Leptin promotes human glioblastoma growth through activating Signal Transducers and Activators of Transcription 3 signaling.
Guosheng Han,Laixing Wang,Zhao Rui,Yue Zhijian,Xiaoping Zhou,Xiaowu Hu,Yiqun Cao,Dongwei Dai,Jianmin Liu +8 more
TL;DR: The data suggest that the JAK/STAT3 signaling pathway may be involved in promoting U87 glioblastoma growth mediated by leptin, which may be a target for anti-neoplastic treatments for gliOBlastoma.
15
Resection of meningiomas with implantable microwave coagulation
TL;DR: Implantable microwave coagulation was used to perform resection on 62 patients that had intracranial meningiomas and it is believed that this new technique has the advantage of simplicity, less blood loss, and smooth postoperative procedures.
7
Chronic high-frequency stimulation therapy in hemiparkinsonian rhesus monkeys using an implanted human DBS system.
TL;DR: It is demonstrated that therapeutically effective human DBS systems can be established in relevant disease models in monkeys and such combination of humanDBS systems in hemiparkinsonian monkeys should be valuable in studying the mechanism of action and chronic consequences of DBS therapy in humans.
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