Xiaomin Yu
Baylor College of Medicine
9 Papers
83 Citations
Xiaomin Yu is an academic researcher from Baylor College of Medicine. The author has contributed to research in topics: Medicine & Viral replication. The author has an hindex of 3, co-authored 6 publications.
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Papers
Human norovirus exhibits strain-specific sensitivity to host interferon pathways in human intestinal enteroids.
Shih-Ching Lin,Lin Qu,Khalil Ettayebi,Sue E. Crawford,Sarah E. Blutt,Matthew J. Robertson,Xi-Lei Zeng,Victoria R. Tenge,B. Vijayalakshmi Ayyar,Umesh C. Karandikar,Xiaomin Yu,Cristian Coarfa,Robert L. Atmar,Sasirekha Ramani,Mary K. Estes +14 more
TL;DR: The findings suggest strain-specific sensitivities to IFN as a factor for global dominance of pandemic strains, provide a new arsenal of stable HIE knockout lines for several IFN pathways, and highlight strain differences as a consideration for development of effective therapies.
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Novel Segment- and Host-Specific Patterns of Enteroaggregative Escherichia coli Adherence to Human Intestinal Enteroids.
Anubama Rajan,Lucy Vela,Xi Lei Zeng,Xiaomin Yu,Noah F. Shroyer,Sarah E. Blutt,Nina M. Poole,Lily G. Carlin,James P. Nataro,Mary K. Estes,Pablo C. Okhuysen,Anthony William Maresso +11 more
TL;DR: Using human intestinal enteroids derived from all four segments of the human intestine, EAEC demonstrates aggregative adherence to duodenal and ileal enteroids, with donor-driven differences driving a sheet-like and layered pattern, implying that the morphology of adherent clusters and the overall intestinal cell association of EAEC occur by different mechanisms.
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Coxsackievirus Group B3 Has Oncolytic Activity against Colon Cancer through Gasdermin E-Mediated Pyroptosis
Yejia Zhang,Tian Xu,Huizhen Tian,Jianfeng Wu,Xiaomin Yu,Lingbing Zeng,Fadi Liu,Qing Liu,Xiaotian Huang +8 more
TL;DR: Zhang et al. as discussed by the authors explored the use of coxsackievirus group B3 (CVB3) as an oncolytic virus for the treatment of colon cancer.
New Insights and Enhanced Human Norovirus Cultivation in Human Intestinal Enteroids.
Khalil Ettayebi,Victoria R. Tenge,Nicolas W. Cortes-Penfield,Sue E. Crawford,Frederick H. Neill,Xi-Lei Zeng,Xiaomin Yu,B. Vijayalakshmi Ayyar,Douglas G. Burrin,Sasirekha Ramani,Robert L. Atmar,Mary K. Estes +11 more
- 27 Jan 2021
TL;DR: HuNoVs are the leading cause of epidemic and sporadic acute gastroenteritis worldwide as mentioned in this paper, and HuNoV is the most common cause of outbreaks of acute and sporadic diarrheal illness in all age groups.
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Enteropathogenic Escherichia coli Infection in Cancer and Immunosuppressed Patients.
Adilene Olvera,Hannah E. Carter,Anubama Rajan,Lily G. Carlin,Xiaomin Yu,Xi Lei Zeng,Samuel A. Shelburne,Micah Bhatti,Sarah E. Blutt,Noah F. Shroyer,Robert R. Jenq,Mary K. Estes,Anthony William Maresso,Pablo C. Okhuysen,Pablo C. Okhuysen +14 more
TL;DR: Immunosuppressed cancer patients with EPEC associated diarrhea carry high burden of EPEC with strains that are resistant to antibiotics, exhibit novel patterns of adherence when studied in HIEs, and interfere with cancer care.
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