Xiaomin Chen
The University of Nottingham Ningbo China
3 Papers
Xiaomin Chen is an academic researcher from The University of Nottingham Ningbo China. The author has contributed to research in topics: Gene knockdown & CD36. The author has an hindex of 2, co-authored 3 publications.
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Papers
LncRNA MALAT1 regulates oxLDL-induced CD36 expression via activating β-catenin.
TL;DR: This work designed and synthesized biotin-TEG labeled oligonucleotides to precipitate the MALAT1 RNA-DNA-protein complex in vivo and found that β-catenin, a transcription factor that promotes CD36 transcription, was found in the complex.
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RBM4 regulates M1 macrophages polarization through targeting STAT1-mediated glycolysis
Ning Huangfu,Wenyuan Zheng,Zhenyu Xu,Shenghuang Wang,Yong Wang,Jingsong Cheng,Zhenwei Li,Ke'ai Cheng,Shuangshuang Zhang,Xiaomin Chen,Jianhua Zhu +10 more
TL;DR: It is reported that R BM4 regulates M1 macrophages polarization through targeting STAT1-mediated glycolysis and shows that RBM4 is a possible candidate for regulating macrophage M1 polarization and inflammatory responses.
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TDP43 Exacerbates Atherosclerosis Progression by Promoting Inflammation and Lipid Uptake of Macrophages.
TL;DR: In this article, the authors investigated whether TDP43 is involved in atherosclerosis development, especially in macrophages-mediated-foam cell formation and inflammatory responses, and they found that specific knockout of TDP-43 in mice with ApoE-/- background were fed with western diet for 12 weeks to establish AS model.