Xiaolong Xu
Ghent University
11 Papers
16 Citations
Xiaolong Xu is an academic researcher from Ghent University. The author has contributed to research in topics: Chemistry & Hydrophilic interaction chromatography. The author has an hindex of 4, co-authored 8 publications.
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Papers
Circular dichroism in functional quality evaluation of medicines.
TL;DR: The basic principles of the CD technique are initially described, followed by a systematic literature research on pharmaceutical aspects encompassing chiral small molecules, bio‐polymers, medicine‐target interaction and medicine changes.
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Photothermal Nanozymatic Nanoparticles Induce Ferroptosis and Apoptosis through Tumor Microenvironment Manipulation for Cancer Therapy.
Haitao Yuan,Penghui Xia,Xin Sun,Jingbo Ma,Xiaolong Xu,Chunjin Fu,Yudong Guan,Zhifen Li,S. W. Zhao,Huifang Wang,Lingyun Dai,Chengchao Xu,Shaohong Dong,Qingshan Geng,Zhi-jie Li,Jigang Wang +15 more
TL;DR: A strategy based on one nanosystem to synergistically induce ferroptosis and apoptosis in vivo for tumor suppression, which holds great potential in the clinical translation for tumor therapy.
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A Surface Acoustic Wave (SAW) biosensor method for functional quantification of E. coli l-asparaginase
TL;DR: This work presents a SAW biosensor based approach for the functional quantification of Escherichia colil-asparaginase, using polyclonal antibody (pAb) as the interaction partner immobilized on the chip, and suggests this SAW method can be adopted as a pharmaceutical QC method.
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Development of a capillary zone electrophoresis method to quantify E. coli L-asparaginase and its acidic variants
Han Yao,Jana Vandenbossche,Cari Sänger van de Griend,Yorick Janssens,Cristina Soto Fernández,Xiaolong Xu,Evelien Wynendaele,Govert W. Somsen,Rob Haselberg,Bart De Spiegeleer +9 more
TL;DR: A capillary zone electrophoresis method with UV detection was developed for the quantification of the E.colil-asparaginase (l-ASNase) and its acidic variants and was validated for linearity, accuracy, precision, LOD, LOQ and robustness.
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Hydrophilic interaction liquid chromatography method development and validation for the assay of HEPES zwitterionic buffer.
TL;DR: A degradant forming under oxidative stressing condition was identified as N‐oxide of HEPES, identified by high resolution MS, and the applicability of the validated method was demonstrated by analysis of samples from different suppliers.
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