18 Papers
22 Citations
Xiaojing Du is an academic researcher from First Affiliated Hospital of Wenzhou Medical University. The author has contributed to research in topics: Medicine & Cancer. The author has an hindex of 8, co-authored 12 publications.
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Papers
FGF/FGFR signaling pathway involved resistance in various cancer types.
TL;DR: The underlying mechanisms of FGF/FGFR signaling mediated resistance to chemotherapy, radiotherapy and target therapy in various cancers are discussed.
Integrated transcriptomic analysis reveals hub genes involved in diagnosis and prognosis of pancreatic cancer
Yang-Yang Zhou,Li-Ping Chen,Yi Zhang,Sun-Kuan Hu,Zhao-Jun Dong,Ming Wu,Qiuxiang Chen,Zhi-Zhi Zhuang,Xiaojing Du +8 more
TL;DR: Integrated transcriptomic analysis identifies two four-hub gene modules as specific predictive signatures for the diagnosis and prognosis of pancreatic cancer, which may bring new sight for the clinical practice of PC.
Da0324, an inhibitor of nuclear factor-κB activation, demonstrates selective antitumor activity on human gastric cancer cells.
Rong Jin,Yiqun Xia,Qiuxiang Chen,Wulan Li,Dahui Chen,Hui Ye,Chengguang Zhao,Xiaojing Du,Dengjian Shi,Jianzhang Wu,Guang Liang +10 more
TL;DR: The asymmetric mono-carbonyl analog of curcumin Da0324 exhibited significantly improved antigastric cancer activity and may be a promising NF-κB inhibitor for the selective targeting of cancer cells.
Loss of GABARAPL1 confers ferroptosis resistance to cancer stem‐like cells in hepatocellular carcinoma
Xiaojing Du,Zhuoran Qi,Jinzhi Xu,Mengzhou Guo,Xingxing Zhang,Zhijie Yu,Xin Cao,Jing-Ling Xia +7 more
TL;DR: A set of ferroptosis‐related stemness genes (FRSG) is identified and it is found that these genes may be involved in immune infiltration in HCC and uncovered a molecular mechanism via which CSLC could achieve tolerance to ferroPTosis.
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Synthesis, biological evaluation, QSAR and molecular dynamics simulation studies of potential fibroblast growth factor receptor 1 inhibitors for the treatment of gastric cancer
Shilong Ying,Xiaojing Du,Weitao Fu,Di Yun,Liping Chen,Yuepiao Cai,Qing Xu,Jianzhang Wu,Wulan Li,Guang Liang +9 more
TL;DR: Evaluation for anti-gastric cancer efficacy of D12 and D15 indicated effective inhibition of cell proliferation, apoptosis induction and cell cycle arrest, and these two FGFR1 inhibitors have therapeutic potential in the treatment of gastric cancer.
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