Xiaohu Ge
Stanford University
8 Papers
17 Citations
Xiaohu Ge is an academic researcher from Stanford University. The author has contributed to research in topics: Stem cell & Induced pluripotent stem cell. The author has an hindex of 5, co-authored 7 publications.
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Papers
Direct Evaluation of Myocardial Viability and Stem Cell Engraftment Demonstrates Salvage of the Injured Myocardium
Paul J Kim,Morteza Mahmoudi,Xiaohu Ge,Yuka Matsuura,Ildiko Toma,Scott A. Metzler,Nigel G. Kooreman,John Ramunas,Colin Holbrook,Michael V. McConnell,Helen M. Blau,Phillip Harnish,Eric Rulifson,Phillip C. Yang +13 more
TL;DR: The functional restoration seen in MiPSCs was characterized by increased myocardial viability and sustained engraftment without de novo cardiac differentiation, indicating salvage of the injured myocardium.
Apelin-13 infusion salvages the peri-infarct region to preserve cardiac function after severe myocardial injury
Wook-Jin Chung,Wook-Jin Chung,Ahryon Cho,Kyunghee Byun,Jeongsik Moon,Xiaohu Ge,Hye-Sun Seo,Ejung Moon,Rajesh Dash,Phillip C. Yang +9 more
TL;DR: A13 preserves cardiac performance by salvaging the peri-infarct region and may contribute to permanent restoration of the severely injured myocardium in murine AMI model.
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MiR-141-3p promotes malignant progression in prostate cancer through AlkB homolog 5-mediated m6A modification of protein arginine methyltransferase 6
TL;DR: Wang et al. as discussed by the authors showed that miR-141-3p accelerated the malignant progression of prostate cancer through ALKBH5-mediated m6A modification of PRMT6.
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Manganese-enhanced MRI detects live human amnion-derived mesenchymal stem cells in vivo after transplantation and restoration of myocardial function in a pig ischemia-reperfusion injury model
Rajesh Dash,Ildiko Toma,Fumiaki Ikeno,Jennifer Lyons,Shahriar Heidary,Marie-Claude Parent,I-Ning E. Wang,Xiaohu Ge,Jaehoon Chung,Justin Lam,Paul J Kim,Kaori Nakagawa,Svetlana Lyalina,Grace Do,Robert C. Robbins,Michael V. McConnell,Alan C. Yeung,Phillip Harnish,Phillip C. Yang +18 more
TL;DR: Human Amnion-derived Mesenchymal Stem Cells were transplanted into the infarct and periinfarct regions of a pig ischemia-reperfusion model and improved cardiac systolic function post-MI, and Cardiac MRI with Manganese-Enhanced MRI was able to detect increased CNR from live populations of hAMSCs.
•Journal Article
Abstract 18108: Performing Dual Contrast Cardiac MRI to Determine the Underlying Mechanism of Cell-based Therapy
TL;DR: The MiPSCs demonstrate the most significant functional restoration and may suggest myocardial regeneration as the mechanism for the sustained benefit of cardiac restorative effects.
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