21 Papers
11 Citations
Xiaogang Wu is an academic researcher from University of Texas MD Anderson Cancer Center. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 2, co-authored 10 publications.
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Papers
Gut microbiome diversity is an independent predictor of survival in cervical cancer patients receiving chemoradiation
Travis T. Sims,Molly B. El Alam,Tatiana Karpinets,Stephanie Dorta-Estremera,Venkatesh Hegde,Sita Nookala,Kyoko Yoshida-Court,Xiaogang Wu,Greyson Biegert,Andrea Y. Delgado Medrano,Travis Solley,Mustapha Ahmed-Kaddar,Bhavana V. Chapman,K. Jagannadha Sastry,Melissa Paola Mezzari,Joseph F. Petrosino,Lilie L. Lin,Lois M. Ramondetta,Anuja Jhingran,Kathleen M. Schmeler,Nadim J. Ajami,Jennifer A. Wargo,Lauren E. Colbert,Ann H. Klopp +23 more
- 22 Feb 2021
TL;DR: Sim Sims et al. as discussed by the authors showed that the diversity of the gut microbiota is associated with a favorable response to chemoradiation and that compositional variation among patients correlated with short term and long-term survival.
Fusobacterium is enriched in oral cancer and promotes induction of programmed death-ligand 1 (PD-L1)
Chieko Michikawa,Vancheswaran Gopalakrishnan,Amani M. Harrandah,Tatiana Karpinets,Rekha R. Garg,Randy A. Chu,Yuk Pheel Park,Sasanka S. Chukkapallia,N. Ganesh Yadlapalli,Kelly C. Erikson-Carter,Frederico O. Gleber-Netto,Elias Sayour,Ann Progulske-Fox,Edward K.L. Chan,Xiaogang Wu,Jianhai Zhang,Christian Jobin,Jennifer A. Wargo,Curtis R. Pickering,Jeffrey L. Myers,Natalie L. Silver +20 more
TL;DR: In this article , the role of oral bacteria in the context of the tumor microenvironment in a single head and neck subsite was investigated, and it was shown that infection with Fusobacterium species can increase both PD-L1 mRNA and surface PD-l1 protein expression.
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Gut Microbiome Alterations Associated with Diabetes in Mexican Americans in South Texas
Suet Ying Kwan,Caroline M. Sabotta,Aron Y. Joon,Peng Wei,Lauren E. Petty,Jennifer E. Below,Xiaogang Wu,Jian Zhang,Robert R. Jenq,Ernest T. Hawk,Joseph B. McCormick,Susan P. Fisher-Hoch,Laura Beretta +12 more
TL;DR: Using samples from a population-based cohort of Mexican Americans with a high prevalence of obesity and diabetes, findings from studies on other ethnicities that suggested promotion of a chronic proinflammatory environment, loss of butyrate production, and compromised intestinal barrier integrity are confirmed.
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A prospective study of the adaptive changes in the gut microbiome during standard-of-care chemoradiotherapy for gynecologic cancers.
Molly B. El Alam,Travis T. Sims,Ramez Kouzy,Greyson Biegert,Joseph Abi Jaoude,Tatiana Karpinets,Kyoko Yoshida-Court,Xiaogang Wu,Andrea Y. Delgado-Medrano,Melissa Paola Mezzari,Nadim J. Ajami,Travis Solley,Mustapha Ahmed-Kaddar,Lilie L. Lin,Lois M. Ramondetta,Amir A. Jazaeri,Anuja Jhingran,Patricia J. Eifel,Kathleen M. Schmeler,Jennifer A. Wargo,Ann H. Klopp,Lauren E. Colbert +21 more
TL;DR: In this article, a prospective study was conducted to identify changes in the diversity and composition of the gut microbiome during and after pelvic chemoradiotherapy (CRT) for cervical, vaginal, or vulvar cancer.
Adaptive changes in the gut microbiome during standard-of-care chemoradiotherapy for gynecologic cancers
Molly B. El Alam,Travis T. Sims,Ramez Kouzy,Greyson Biegert,Joseph Abi Jaoude,Tatiana Karpinets,Kyoko Yoshida Court,Xiaogang Wu,Andrea Y. Delgado Medrano,Melissa Mezzari,Nadim J. Ajami,Travis Solley,Mustapha Ahmed-Kaddar,Lilie L. Lin,Lois M. Ramondetta,Amir Jazaeria,Anuja Jhingran,Patricia J. Eifel,Kathleen M. Schmeler,Jennifer A. Wargo,Ann H. Klopp,Lauren E. Colbert +21 more
TL;DR: Gut microbiome richness and diversity levels continually decreased throughout CRT, but were at or near baseline levels in 60% of patients by week 12, and changes should be considered when designing studies to analyze the gut microbiome as a predictive or prognostic biomarker in patients who receive pelvic CRT for gynecologic cancers.
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