Xiaofeng Yang
Xi'an Jiaotong University
35 Papers
56 Citations
Xiaofeng Yang is an academic researcher from Xi'an Jiaotong University. The author has contributed to research in topics: Cervical cancer & Internal medicine. The author has an hindex of 8, co-authored 27 publications.
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Papers
Crosstalk between histone modification and DNA methylation orchestrates the epigenetic regulation of the costimulatory factors, Tim‑3 and galectin‑9, in cervical cancer.
Li Zhang,Sijuan Tian,Meili Pei,Minyi Zhao,Li Wang,Yifan Jiang,Ting Yang,Juan Zhao,Lihua Song,Xiaofeng Yang +9 more
TL;DR: It is suggested that EZH2, H3K27me3 and DNMT3A mediate the epigenetic regulation of the negative stimulatory molecules, Tim-3 and galectin-9 in cervical cancer which is associated with HPV18 infection.
SUV39H1-DNMT3A-mediated epigenetic regulation of Tim-3 and galectin-9 in the cervical cancer
TL;DR: In an in vivo assay, the expression profile of SUV39H1 up-regulates the level of H3K9me3 at the DNMT3A promoter region, which was found to correlate with Tim-3 and galectin-9 cellular expression level.
Negative immune factors might predominate local tumor immune status and promote carcinogenesis in cervical carcinoma
Minyi Zhao,Yang Li,Xing Wei,Qian Zhang,Hongran Jia,Shimin Quan,Di Cao,Li Wang,Ting Yang,Juan Zhao,Meili Pei,Sijuan Tian,Yang Yu,Yanping Guo,Xiaofeng Yang +14 more
TL;DR: It may be that, in microenvironment of cervical squamous cell carcinoma, negative immune regulators FoxP3, CCL22 and CCR4 might overwhelm positive immune factors OX40L, Ox40 and Smad3, giving rise to an immunosuppressive status and promote the progression of cervical carcinogenesis.
Aberrant Hypermethylation of SALL3 with HPV Involvement Contributes to the Carcinogenesis of Cervical Cancer
Xing Wei,Shaohua Zhang,Di Cao,Minyi Zhao,Qian Zhang,Juan Zhao,Ting Yang,Meili Pei,Li Wang,Yang Li,Xiaofeng Yang +10 more
TL;DR: The aberrant hypermethylation of SALL3 together with HPV involvement inactivated its function as a tumor suppressor and contributed to carcinogenesis in cervical cancer.
Effects of vitamin D supplementation on metabolic parameters of women with polycystic ovary syndrome: a meta-analysis of randomized controlled trials.
TL;DR: The results of this meta-analysis suggested that vitamin D supplementation decreases fasting glucose concentration and total cholesterol concentration in PCOS women with vitamin D deficiency.
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