Xiaofei Wang
Shanghai Jiao Tong University
8 Papers
26 Citations
Xiaofei Wang is an academic researcher from Shanghai Jiao Tong University. The author has contributed to research in topics: Proinflammatory cytokine & Lung cancer. The author has an hindex of 8, co-authored 8 publications. Previous affiliations of Xiaofei Wang include National Cancer Research Institute.
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Papers
The G-Protein-Coupled Chemoattractant Receptor Fpr2 Exacerbates High Glucose-Mediated Proinflammatory Responses of Müller Glial Cells.
Ying Yu,Zhiyao Bao,Xiaofei Wang,Xiaofei Wang,Wanghua Gong,Hui Chen,Huaijin Guan,Yingying Le,Shaobo Su,Keqiang Chen,Ji Ming Wang +10 more
TL;DR: The results suggest that Fpr2, together with FGFR1, may actively participate in the pathogenesis of PDR thus may be considered as one of the potential therapeutic targets.
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Metformin sensitizes lung cancer cells to treatment by the tyrosine kinase inhibitor erlotinib.
Xiaofei Wang,Keqiang Chen,Ying Yu,Ying Yu,Yi Xiang,Jae Hong Kim,Wanghua Gong,Jiaqiang Huang,Guochao Shi,Qingyun Li,Min Zhou,Thomas J. Sayers,Poonam Tewary,Beili Gao,Ji Ming Wang +14 more
TL;DR: In this paper, a combination of metformin and erlotinib (Erlo) was found to more efficiently inhibited the growth of lung cancer cells both in vitro and in mice with xenografted tumors.
Epithelial Neoplasia Coincides with Exacerbated Injury and Fibrotic Response in the Lungs of Gprc5a -Knockout Mice Following Silica Exposure
Xiaofei Wang,Dongliang Xu,Yueling Liao,Shuangshuang Zhong,Hongyong Song,Beibei Sun,Binhua P. Zhou,Jiong Deng,Baohui Han +8 more
TL;DR: The results suggest that the process of tissue repair coincides with tissue damages; whereas persistent tissue damages leads to abnormal repair or neoplasia in lungs from Gprc5a−/− mouse model.
G9a is essential for EMT-mediated metastasis and maintenance of cancer stem cell-like characters in head and neck squamous cell carcinoma
Shuli Liu,Dongxia Ye,Wenzheng Guo,Wenwen Yu,Yue He,Jingzhou Hu,Yanan Wang,Lingling Zhang,Yueling Liao,Hongyong Song,Shuangshuang Zhong,Dongliang Xu,Huijing Yin,Beibei Sun,Xiaofei Wang,Jingyi Liu,Yadi Wu,Binhua P. Zhou,Zhiyuan Zhang,Jiong Deng +19 more
TL;DR: It is found that G9a, a histone methyltransferase, interacts with Snail and mediates Snail-induced transcriptional repression of E-cadherin and EMT, through methylation of histone H3 lysine-9 (H3K9).