Xiaodong Wang
University of California, San Francisco
5 Papers
18 Citations
Xiaodong Wang is an academic researcher from University of California, San Francisco. The author has contributed to research in topics: Bone healing & Cellular differentiation. The author has an hindex of 5, co-authored 5 publications.
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Papers
Multiple roles for CCR2 during fracture healing
Zhiqing Xing,Chuanyong Lu,Diane Hu,Yan Yiu Yu,Xiaodong Wang,Céline Colnot,Mary C. Nakamura,Yalei Wu,Theodore Miclau,Ralph S. Marcucio +9 more
TL;DR: Results indicate that a deficiency of Ccr2 reduces the infiltration of macrophages and impairs the function of osteoclasts, leading to delayed fracture healing.
MMP9 regulates the cellular response to inflammation after skeletal injury
Xiaodong Wang,Yan Yiu Yu,Shirley Lieu,Frank Yang,Jeffrey Lang,Chuanyong Lu,Zena Werb,Diane Hu,Theodore Miclau,Ralph S. Marcucio,Céline Colnot,Céline Colnot +11 more
TL;DR: Results show that MMP9 mediates indirect effects on skeletal cell differentiation by regulating the inflammatory response and the distribution of inflammatory cells, leading to the local regulation of periosteal cell differentiation.
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Anti-inflammatory treatment increases angiogenesis during early fracture healing
Chuanyong Lu,Chuanyong Lu,Zhiqing Xing,Xiaodong Wang,Jeremy J. Mao,Ralph S. Marcucio,Theodore Miclau +6 more
TL;DR: Anti-inflammatory treatments using indomethacin impair bone and cartilage formation and increase tissue vascularization in the callus during early fracture healing.
19
The role of oxygen during fracture healing
Chuanyong Lu,Neema Saless,Xiaodong Wang,Arjun Sinha,Sebastian Decker,Galateia J. Kazakia,Huagang Hou,Benjamin B. Williams,Harold M. Swartz,Thomas K. Hunt,Theodore Miclau,Ralph S. Marcucio +11 more
TL;DR: It is indicated that environmental oxygen levels affect tissue vascularization and fracture healing, and that providing oxygen when fractures are accompanied by ischemia may be beneficial.
Mechanical Stability Affects Angiogenesis During Early Fracture Healing
Chuanyong Lu,Neema Saless,Diane Hu,Xiaodong Wang,Zhiqing Xing,Huagang Hou,Benjamin B. Williams,Harold M. Swartz,Celine Colnot,Celine Colnot,Theodore Miclau,Ralph S. Marcucio +11 more
TL;DR: The authors found that new blood vessel formation was robust by 3 days after fracture, suggesting that nonstabilized fractures were more vascularized, and mechanical instability promotes angiogenesis during early fracture healing.