Xiaoding Liu
Peking Union Medical College Hospital
16 Papers
9 Citations
Xiaoding Liu is an academic researcher from Peking Union Medical College Hospital. The author has contributed to research in topics: Pancreatic cancer & Medicine. The author has an hindex of 3, co-authored 10 publications.
Chat about Author
Papers
Upregulation of nucleoprotein AHNAK is associated with poor outcome of pancreatic ductal adenocarcinoma prognosis via mediating epithelial-mesenchymal transition
TL;DR: AHNAK is a crucial biomarker that may promote cellular proliferation and migration and thus impact PDAC outcomes via the EMT, which suggests that AHANK might be a potential target for PDAC.
Noninvasive detection of pancreatic ductal adenocarcinoma using the methylation signature of circulating tumour DNA
Huanwen M. Wu,Shiwei Guo,Xiaoding Liu,Yatong Li,Zhixi Su,Qiye He,Xiaoqian Liu,Zhiwen Zhang,Lianyuan Yu,Xiaohan Shi,Suizhi Gao,Huan Wang,Yaqi Pan,Chengcheng Ma,Rui Liu,Menghua Dai,Gang Jin,Zhiyong Liang +17 more
TL;DR: In this paper , a non-invasive test for early PDAC detection by capturing the circulating tumour DNA (ctDNA) methylation signature in blood was developed, which achieved an area under the curve (AUC) of 0.91 in both the validation and independent tests.
Pancreatic stellate cells exploit Wnt/β-catenin/TCF7-mediated glutamine metabolism to promote pancreatic cancer cells growth.
Hangqi Liu,Hui Zhang,Xiaoqian Liu,Wenting Guo,Qiaofei Liu,Long-Fong Chen,Junyi Pang,Xiaoding Liu,Ruiyu Li,Weimin Tong,Huanwen M. Wu,Menghua Dai,Zhiyong Liang +12 more
TL;DR: Wang et al. as mentioned in this paper showed that tumor tissues displayed Gln deficiency in orthotopic PDAC models and showed that increased Gln secreted by PSCs increased basal oxygen consumption rate in PCCs.
26
RNA sequencing reveals novel oncogenic fusions and depicts detailed fusion transcripts of FN1-FGFR1 in phosphaturic mesenchymal tumors.
Xiaoding Liu,Kaimi Li,Hui Zhang,Junliang Lu,Liangrui Zhou,Jie Gao,Jing Wang,Huanwen M. Wu,Zhiyong Liang +8 more
TL;DR: Fusion transcripts and breakpoints of FN1::FGFR1 in PMTs are reported in detail, providing insights into fusion protein functions, and it is revealed that a considerable proportion of PMTs without FN1 ::FG FR1 fusion carried novel fusions, providing further insight into the genetic basis of PM Ts.
7
A new prognosis prediction model combining TNM stage with MAP2K4 and JNK in postoperative pancreatic cancer patients.
TL;DR: This study shows that reduced protein and mRNA levels of MAP2K4 found in PDAC patients, coupled to in vitro effects observed, support the tumor suppressor role of MAP 2K4 inPDAC.
6