Xiaochen Wei
University of Kentucky
10 Papers
59 Citations
Xiaochen Wei is an academic researcher from University of Kentucky. The author has contributed to research in topics: Dehydrogenation & Dopamine. The author has an hindex of 6, co-authored 10 publications.
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Papers
Identification and synthesis of novel alkaloids from the root system of Nicotiana tabacum: affinity for neuronal nicotinic acetylcholine receptors.
Xiaochen Wei,Sangeetha P. Sumithran,A. Gabriela Deaciuc,Harold R. Burton,Lowell P. Bush,Linda P. Dwoskin,Peter A. Crooks +6 more
TL;DR: A novel pyridine derivative, 3,5-bis-(1-methyl-pyrrolidin-2-yl)-pyridine, and a pair of diastereomers of 1,1'-dimethyl-[2,3']bipyrrolidsinyl were isolated from the root of Nicotiana tabacum plants and identified as novel alkaloids by GC-MS analysis.
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Patent
Use of parthenolide derivatives as antileukemic and cytotoxic agents
Peter A. Crooks,Craig T. Jordan,Xiaochen Wei +2 more
- 09 Jul 2004
TL;DR: In this article, the present invention provides compounds of the formula (I) wherein: X 1, X 2 and X 3 are heteroatoms; R 4, R 5, R 6, R 7, R 8, R 9 and R 10 are independently selected from H, halo, NO 2, CN and optionally substituted aliphatic, cycloalkyl, aryl or heteroaryl.
Elimination of alkaloids from plant-derived human monoclonal antibody.
TL;DR: A human antiviral monoclonal antibody expressed in transgenic tobacco plants was purified from the tobacco leaf by two different methods and exhibited higher binding activity compared to immunoprecipitation-derived product against rabies virus strain CVS-11 in ELISA.
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Effects of nornicotine enantiomers on intravenous S(−)-nicotine self-administration and cardiovascular function in rats
Dustin J. Stairs,Nichole M. Neugebauer,Xiaochen Wei,Carine M Boustany,Marhaba Hojahmat,Lisa A. Cassis,Peter A. Crooks,Linda P. Dwoskin,Michael T. Bardo +8 more
TL;DR: Both R(+)- and S(−)-nornicotine may have potential utility as a novel tobacco use cessation agent.
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Smoking risk and the likelihood of quitting among African-American female light and heavy smokers.
TL;DR: The study found that African- American female light smokers take longer to smoke their first cigarette of the day, have a lower smoking risk, are more likely to quit, and exhibit lower carbon monoxide levels than African-American female heavy smokers.
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