Xiaobin Lu
Saint Louis University
6 Papers
24 Citations
Xiaobin Lu is an academic researcher from Saint Louis University. The author has contributed to research in topics: Spinal cord & Schwann cell. The author has an hindex of 5, co-authored 6 publications.
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Papers
Neurotrophins BDNF and NT-3 promote axonal re-entry into the distal host spinal cord through Schwann cell-seeded mini-channels.
TL;DR: It is demonstrated that regenerating axons not only cross a lesion site when a permissive cellular bridge is provided but also penetrate into the distal host spinal cord and elongate for a distance of several cord segments after the infusion of two neurotrophins.
222
White Matter Injury in Spinal Cord Ischemia: Protection by AMPA/Kainate Glutamate Receptor Antagonism
Georgios K. Kanellopoulos,Xiao Ming Xu,Chung Y. Hsu,Xiaobin Lu,Thoralf M. Sundt,Nicholas T. Kouchoukos +5 more
TL;DR: In this article, the effects of AMPA/kainate receptor blockade on ischemic white matter injury in a rat model of spinal cord ischemia was studied, and the effect of 6-nitro-7-sulfamoyl-(f)-quinoxaline-2,3-dione (NBQX) was shown to reduce locomotor deficit.
106
Neural circuitry of the adult rat central nervous system after spinal cord injury: A study using fast blue and the Bartha strain of pseudorabies virus
TL;DR: A proportion of neural network across the injured spinal cord has been spared after acute contusive SCI, the proportion of spared axons of a particular pathway is closely correlated to the injury severity and the position of that pathway, and the transneuronal labeling method using PRV may provide a unique approach to investigate multi-synaptic neural circuitry of the central autonomic control after SCI.
24
Neurotrophins BDNF and NT-3 promote axonal re-entry into the distal host spinal cord through Schwann cell-seeded mini-channels: BDNF and NT-3 promote axonal regrowth after SCI
TL;DR: It is demonstrated that regenerating axons not only cross a lesion site when a permissive cellular bridge is provided but also penetrate into the distal host spinal cord and elongate for a distance of several cord segments after the infusion of two neurotrophins.
16
Glial cell line-derived neurotrophic factor-enriched bridging transplants promote propriospinal axonal regeneration and enhance myelination after spinal cord injury.
Christopher Iannotti,Huayin Li,Ping Yan,Xiaobin Lu,Louisa Wirthlin,Xiao Ming Xu,Xiao Ming Xu +6 more
TL;DR: Results indicate that GDNF may play a novel therapeutic role in promoting propriospinal axonal regeneration, enhancing myelin formation, and improving graft-host interfaces after SCI.