Xiao Wang
Huaqiao University
16 Papers
18 Citations
Xiao Wang is an academic researcher from Huaqiao University. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 5, co-authored 9 publications.
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Papers
The Structure and Pharmacological Functions of Coumarins and Their Derivatives
TL;DR: This review will focus on recent advances in molecular and cellular mechanisms of coumarin action involved with the relationship between structure and activity.
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Evaluation of anti-inflammatory and antinociceptive activities of Murraya exotica
TL;DR: E ethanol (70%) extracts significantly decreased in the acetic acid-induced writhing response; increased in hot-plate latency; suppressed xylene induced ear swelling and the carrageenan-induced paw edema effectively; and exhibited remarkable antinociceptive and anti-inflammatory activities.
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Tubulin degradation: Principles, agents, and applications.
TL;DR: In this article , the authors reviewed the reports on tubulin degradation, and focused on the degradation mechanism and important functional groups of chemically synthesized compounds, hoping to provide help for the degradation design of tubulin.
13
Cell surface expression of nucleolin mediates the antiangiogenic and antitumor activities of kallistatin.
Xiaoping Huang,Xiao Wang,Xiaolan Xie,Gao-Ping Zhang,Feng-Jiao Lv,Wen-Ting Weng,Fei Qiu,Zhao-Fa Li,Junsheng Lin,Yong Diao +9 more
TL;DR: It is demonstrated that nucleolin is a novel functional receptor of kallistatin that mediates its antiangiogenic and antitumor activities and provides mechanistic insights into the inhibitory effects of k allistatin on endothelial cell growth, tumor cell proliferation, and tumor-related angiogenesis.
Inhibition of integrin β3, a binding partner of kallistatin, leads to reduced viability, invasion and proliferation in NCI-H446 cells.
Guo-Quan Wang,Xiao Wang,Xiaoping Huang,Xiaoping Huang,Xiaoping Huang,Huiyong Yang,Suqiu Pang,Xiaolan Xie,Shulan Zeng,Junsheng Lin,Yong Diao +10 more
TL;DR: These findings reveal a novel role for kallistatin in preventing small cell lung cancer growth and mobility, by direct interaction with integrin β3, leading to blockade of the related signaling pathway.
10