Xiao Ming Xu
Indiana University
245 Papers
1.3K Citations
Xiao Ming Xu is an academic researcher from Indiana University. The author has contributed to research in topics: Spinal cord injury & Spinal cord. The author has an hindex of 55, co-authored 241 publications. Previous affiliations of Xiao Ming Xu include Washington University in St. Louis & Second Military Medical University.
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Papers
Axonal regeneration into Schwann cell‐seeded guidance channels grafted into transected adult rat spinal cord
TL;DR: Testing the ability of SC to enhance axonal regeneration in adult rat spinal cord by grafting SC‐seeded guidance channels into transected cords found purified populations of SC transplanted within channels promote both propriospinal and sensory axonal regenerate in the adult rat thoracic spinal cord.
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Functional recovery in traumatic spinal cord injury after transplantation of multineurotrophin-expressing glial-restricted precursor cells.
Qilin Cao,Xiao Ming Xu,William H. DeVries,Gaby Enzmann,Peipei Ping,Peipei Ping,Pantelis Tsoulfas,Patrick M. Wood,Mary Bartlett Bunge,Scott R. Whittemore +9 more
TL;DR: Combined treatment with neurotrophins and GRP grafts can facilitate functional recovery after traumatic SCI and may prove to be a useful therapeutic strategy to repair the injured spinal cord.
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Altered MicroRNA Expression following Traumatic Spinal Cord Injury
TL;DR: The bioinformatics analysis indicates that the potential targets for miRNAs altered after SCI include genes encoding components that are involved in the inflammation, oxidation, and apoptosis that are known to play important roles in the pathogenesis of SCI.
306
Suppression of inflammatory and neuropathic pain by uncoupling CRMP-2 from the presynaptic Ca2+ channel complex
Joel M. Brittain,Djane B. Duarte,Sarah M. Wilson,Weiguo Zhu,Carrie J. Ballard,Philip L. Johnson,Nai-Kui Liu,Wenhui Xiong,Matthew S. Ripsch,Yuying Wang,Jill C. Fehrenbacher,Stephanie D. Fitz,May Khanna,Chul Park,Brian S. Schmutzler,Bo M. Cheon,Michael R. Due,Tatiana Brustovetsky,Nicole M. Ashpole,Andy Hudmon,Samy O. Meroueh,Cynthia M. Hingtgen,Nickolay Brustovetsky,Ru-Rong Ji,Joyce H. Hurley,Xiaoming Jin,Anantha Shekhar,Xiao Ming Xu,Gerry Stephen Oxford,Michael R. Vasko,Fletcher A. White,Rajesh Khanna +31 more
TL;DR: By preventing CRMP-2–mediated enhancement of CaV2.2 function, TAT-CBD3 alleviated inflammatory and neuropathic hypersensitivity, an approach that may prove useful in managing chronic pain.
Neurotrophins BDNF and NT-3 promote axonal re-entry into the distal host spinal cord through Schwann cell-seeded mini-channels.
TL;DR: It is demonstrated that regenerating axons not only cross a lesion site when a permissive cellular bridge is provided but also penetrate into the distal host spinal cord and elongate for a distance of several cord segments after the infusion of two neurotrophins.
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