Xianzhen Yin
Southwest Jiaotong University
5 Papers
Xianzhen Yin is an academic researcher from Southwest Jiaotong University. The author has contributed to research in topics: Macrophage polarization & Cytokine. The author has an hindex of 3, co-authored 4 publications.
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Papers
Macrophage phenotype switch by sequential action of immunomodulatory cytokines from hydrogel layers on titania nanotubes.
TL;DR: A system of double hydrogel layers on titania nanotubes was prepared as reservoir to modulate the release of interleukin-4 (IL-4) and interferon-γ (IFN-γ) and might be used to research immune response between tissues and implants.
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Alginate/chitosan modified immunomodulatory titanium implants for promoting osteogenesis in vitro and in vivo
TL;DR: In vivo studies in rat bone defect model revealed that IL-4-loaded immunomodulatory implants successfully achieved macrophage phenotypic transition from pro- inflammatory M1 to anti-inflammatory M2 and subsequently improved new bone formation.
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Inflammatory responses to micro/nano-structured titanium surfaces with silver nanoparticles in vitro
TL;DR: In this article, the effect of antibacterial materials on macrophage polarization was investigated in micro/nano-structured titanium (MNT) implant using micro-arc oxidization.
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IL-4-loaded alginate/chitosan multilayer films for promoting angiogenesis through both direct and indirect means
TL;DR: In this paper , a cytokine-controlled release system was employed, and the effects thereof on angiogenesis through both direct and indirect means were investigated, where Alginate/chitosan multilayer films were fabricated on interleukin (IL)-4loaded titania nanotubes to achieve a sustained release of IL-4.
Alginate/chitosan multilayer films coated on IL-4-loaded TiO2 nanotubes for modulation of macrophage phenotype
TL;DR: IL-4 was controlled released from the cross-linked PEM films deposited on the nanotubes, leading to the temporal conversion of macrophage phenotype, and indicated that IL-4-loaded Pem films significantly attenuated the inflammatory activity of Macrophages at the later stage through down-regulating the mRNA and protein levels of inflammatory markers.