Xiangpeng Wang
Northwest A&F University
8 Papers
31 Citations
Xiangpeng Wang is an academic researcher from Northwest A&F University. The author has contributed to research in topics: Porcine reproductive and respiratory syndrome virus & Virus. The author has an hindex of 7, co-authored 8 publications. Previous affiliations of Xiangpeng Wang include Chinese Ministry of Agriculture.
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Papers
PK-15 cells transfected with porcine CD163 by PiggyBac transposon system are susceptible to porcine reproductive and respiratory syndrome virus.
Xiangpeng Wang,Ruifang Wei,Qiongyi Li,Hongliang Liu,Baicheng Huang,Jiming Gao,Yang Mu,Chengbao Wang,Walter H. Hsu,Julian A. Hiscox,En-Min Zhou +10 more
TL;DR: In this paper, the PiggyBac (PB) transposon system is applied to porcine reproductive and respiratory syndrome virus (PRRSV) infection assays and the results showed that the average transgene copy number per genome was approximately 10.
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Intracellularly expressed nanobodies against non-structural protein 4 of porcine reproductive and respiratory syndrome virus inhibit virus replication.
TL;DR: Nanobodies hold great potential for development as novel antiviral treatments for PRRSV infection and are isolated from a phage display library of the variable domains of camelid heavy chain-only antibodies.
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Glycoprotein 5 of porcine reproductive and respiratory syndrome virus strain SD16 inhibits viral replication and causes G2/M cell cycle arrest, but does not induce cellular apoptosis in Marc-145 cells
Yang Mu,Yang Mu,Liangliang Li,Liangliang Li,Beibei Zhang,Beibei Zhang,Baicheng Huang,Baicheng Huang,Jiming Gao,Jiming Gao,Xiangpeng Wang,Xiangpeng Wang,Chengbao Wang,Chengbao Wang,Shuqi Xiao,Shuqi Xiao,Qin Zhao,Qin Zhao,Yani Sun,Yani Sun,Gaiping Zhang,Gaiping Zhang,Julian A. Hiscox,Julian A. Hiscox,En-Min Zhou,En-Min Zhou +25 more
TL;DR: It is suggested that PRRSV GP5 is not responsible for inducing cell apoptosis in Marc-145 cells under these experimental conditions; however it has other important roles in virus/host cell biology.
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GP5 expression in Marc-145 cells inhibits porcine reproductive and respiratory syndrome virus infection by inducing beta interferon activity.
Jiming Gao,Jiming Gao,Pengchao Ji,Pengchao Ji,Maodong Zhang,Maodong Zhang,Xiangpeng Wang,Xiangpeng Wang,Na Li,Chengbao Wang,Chengbao Wang,Shuqi Xiao,Shuqi Xiao,Yang Mu,Yang Mu,Qin Zhao,Qin Zhao,Taofeng Du,Taofeng Du,Yani Sun,Yani Sun,Julian A. Hiscox,Gaiping Zhang,Gaiping Zhang,En-Min Zhou,En-Min Zhou +25 more
TL;DR: Data suggest that early GP5 expression is not favorable for further infection by PRRSV, because it not only stimulates production of neutralization antibodies in pigs, but also induces IFN-β production in host cells.
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Intracellular expression of an anti-idiotypic antibody single-chain variable fragment reduces porcine reproductive and respiratory syndrome virus infection in MARC-145 cells.
Qiongyi Li,Xiangpeng Wang,Chengbao Wang,Ying Yu,Gang Wang,Jiming Gao,Hongliang Liu,Huali Xie,Baicheng Huang,Zhijun Li,Ning Kong,Gaiping Zhang,Walter H. Hsu,En-Min Zhou +13 more
TL;DR: The expression of the anti-idiotypic antibody 5G2scFv in MARC-145 cells has the interferential effect on PRRSV infection in the cells by induction of IFN-α, which provides a novel therapeutic approach for PR RSV infection.
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