Xia Yang
Sichuan University
18 Papers
33 Citations
Xia Yang is an academic researcher from Sichuan University. The author has contributed to research in topics: Chemistry & Medicine. The author has an hindex of 8, co-authored 11 publications.
Chat about Author
Papers
Multitarget drug design strategy against Alzheimer’s disease: Homoisoflavonoid Mannich base derivatives serve as acetylcholinesterase and monoamine oxidase B dual inhibitors with multifunctional properties
Yan Li,Xiaoming Qiang,Li Luo,Xia Yang,Ganyuan Xiao,Yunxiaozhu Zheng,Zhongcheng Cao,Zhipei Sang,Fu Su,Yong Deng +9 more
TL;DR: In this article, a series of homoisoflavonoid Mannich base derivatives were designed, synthesized and evaluated as multifunctional agents against Alzheimer's disease, and it demonstrated that most of the derivatives were selective AChE and MAO-B dual inhibitors.
70
Aurone Mannich base derivatives as promising multifunctional agents with acetylcholinesterase inhibition, anti-β-amyloid aggragation and neuroprotective properties for the treatment of Alzheimer's disease.
Yan Li,Xiaoming Qiang,Li Luo,Xia Yang,Ganyuan Xiao,Qi Liu,Jiachen Ai,Zhenghuai Tan,Yong Deng +8 more
TL;DR: Compound 7d displayed high antioxidant activity and could confer significant neuroprotective effect against H2O2-induced PC-12 cell injury and is highlighted as promising candidate for further studies directed to the development of novel drugs against AD.
70
Multifunctional thioxanthone derivatives with acetylcholinesterase, monoamine oxidases and β-amyloid aggregation inhibitory activities as potential agents against Alzheimer's disease.
Li Luo,Yan Li,Xiaoming Qiang,Zhongcheng Cao,Xu Rui,Xia Yang,Ganyuan Xiao,Qing Song,Zhenghuai Tan,Yong Deng +9 more
TL;DR: A series of 1-hydroxyl-3-aminoalkoxy-thioxanthone derivatives were designed, synthesized and evaluated as potential multifunctional agents against Alzheimer's disease (AD) as mentioned in this paper.
29
MicroRNA-21 electrochemiluminescence biosensor based on Co-MOF–N-(4-aminobutyl)-N-ethylisoluminol/Ti3C2Tx composite and duplex-specific nuclease-assisted signal amplification
Yang Jiang,R. Li,Wenyu He,Qiang Li,Xia Yang,Sijia Li,Wanqiao Bai,Yan Li +7 more
- 01 Mar 2022
TL;DR: The designed ECL biosensor can detect miRNA-21 extracted from HeLa cells, indicating its promising application in clinical diagnosis and disease prognosis analysis.
14
Challenges in the Diagnosis of Epstein-Barr Virus-positive Inflammatory Follicular Dendritic Cell Sarcoma
Yan Li,Xia Yang,LiLi Tao,Wei-Fang Zeng,Min Zuo,Shuo Li,Liyan Wu,Yanshong Lin,Ziying Zhang,Jingping Yun,Yuhua Huang +10 more
TL;DR: In this article , the authors investigated the wide morphologic spectrum and immunophenotype of Epstein-Barr virus (EBV)-positive inflammatory follicular dendritic cell (FDC) sarcoma with the aim to help avoid misdiagnosis.
9