Xia Guo
Xinjiang Medical University
5 Papers
42 Citations
Xia Guo is an academic researcher from Xinjiang Medical University. The author has contributed to research in topics: Atrial fibrillation & Repolarization. The author has an hindex of 4, co-authored 5 publications.
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Papers
Accelerated fibrosis and apoptosis with ageing and in atrial fibrillation: Adaptive responses with maladaptive consequences
Guo-Jun Xu,Tian-Yi Gan,Baopeng Tang,Zu-Heng Chen,Ailiman Mahemuti,Tao Jiang,Jian-Guo Song,Xia Guo,Yao-Dong Li,Hai-jun Miao,Xianhui Zhou,Yu Zhang,Jin-Xin Li +12 more
TL;DR: Samples of atrial tissue demonstrated abnormal pathohistological and ultrastructural changes, accelerated fibrosis and apoptosis, and MMP-9/TIMP-1 and BCL-2/BAX hold potential for use as substrates conducive to AF and their abnormal expression plays a major role in structural remodeling of the atrium.
•Journal Article
Changes in microRNAs expression are involved in age-related atrial structural remodeling and atrial fibrillation.
Guo-Jun Xu,Tian-Yi Gan,Baopeng Tang,Zu-Heng Chen,Mahemuti Ailiman,Xianhui Zhou,Tao Jiang,Jian-Guo Song,Xia Guo,Yaodong Li,Hai-jun Miao,Yu Zhang,Jinxin Li +12 more
TL;DR: These multiple aberrantly expressed microRNAs may be responsible for modulating the transition from adaptation to pathological atrial remodeling with aging and/or in AF.
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Expression of tyrosine hydroxylase and growth-associated protein 43 in aging patients with atrial fibrillation of Xinjiang Uygur and Han nationalities
Yao-Dong Li,Jin-Xin Li,Baopeng Tang,Tian-Yi Gan,Guo-Jun Xu,Xianhui Zhou,Hui Li,Xia Guo,Ailiman Mahemuti,Qi Sun,Yan-Yi Zhang,Jiang Wang +11 more
TL;DR: The increase in the expression of TH and GAP43 may be one of the molecular bases of the left atrial myoelectricity remodeling of aging patients with atrial fibrillation.
Alterations in the expression of atrial calpains in electrical and structural remodeling during aging and atrial fibrillation
Guo-Jun Xu,Tian-Yi Gan,Baopeng Tang,Zu-Heng Chen,Ailiman Mahemuti,Tao Jiang,Jian-Guo Song,Xia Guo,Yao-Dong Li,Xianhui Zhou,Yu Zhang,Jin-Xin Li +11 more
TL;DR: Samples of atrial tissue exhibited abnormal histopathological and ultrastructural changes, such as accelerated fibrosis and apoptosis with aging and in AF, which may produce a substrate that is conducive to AF.
Age-related changes in cellular electrophysiology and calcium handling for atrial fibrillation
TL;DR: It is concluded that ageing‐induced electrophysiological and molecular changes showed that general pathophysiological adaptations might provide a substrate conducive to AF.