Xi Wang
Dartmouth College
11 Papers
10 Citations
Xi Wang is an academic researcher from Dartmouth College. The author has contributed to research in topics: Aspergillus fumigatus & Biology. The author has an hindex of 2, co-authored 6 publications.
Chat about Author
Papers
MDA5 Is an Essential Sensor of a Pathogen-Associated Molecular Pattern Associated with Vitality That Is Necessary for Host Resistance against Aspergillus fumigatus.
Xi Wang,Alayna K. Caffrey-Carr,Alayna K. Caffrey-Carr,Ko-Wei Liu,Vanessa Espinosa,Walburga Croteau,Sourabh Dhingra,Amariliz Rivera,Robert A. Cramer,Joshua J. Obar +9 more
TL;DR: It is demonstrated that MDA5/MAVS signaling was essential for host resistance against pulmonary Aspergillus fumigatus challenge through the regulation of antifungal leukocyte responses in mice, and the role of the RLR family is broadened to include a role in regulating antIFungal immunity against A. fumgatus.
21
Aspergillus fumigatus Strain-Specific Conidia Lung Persistence Causes an Allergic Broncho-Pulmonary Aspergillosis-Like Disease Phenotype
Jane T. Jones,Ko-Wei Liu,Xi Wang,Caitlin H. Kowalski,Brandon S. Ross,Kathleen A. M. Mills,Kathleen A. M. Mills,Joshua D. Kerkaert,Tobias M. Hohl,Tobias M. Hohl,Lotus A. Lofgren,Jason E. Stajich,Joshua J. Obar,Robert A. Cramer +13 more
- 17 Feb 2021
TL;DR: In this article, the authors identify a strain of Aspergillus fumigatus resistant to leukocyte-mediated killing and persisted in the mouse lung longer than CEA10, a phenotype that correlated with greater resistance to oxidative stressors, hydrogen peroxide, and menadione.
MAVS expression in alveolar macrophages is essential for host resistance against Aspergillus fumigatus
Xi Wang,Cristina Cunha,Madeleine S. Grau,Shelly J. Robertson,João F. Lacerda,António Campos,Katrien Lagrou,Johan Maertens,Sonja M. Best,Agostinho Carvalho,Joshua J. Obar +10 more
TL;DR: In this article, the role of the RIG-I-like receptor (RLR) family in regulating antifungal immunity against Aspergillus fumigatus in a murine model was demonstrated.
A humanized anti-human adenovirus 55 monoclonal antibody with good neutralization ability
Lei Chen,Jiansheng Liu,Junjie Yue,Rong Wang,Peng Du,Yunzhou Yu,Jiazheng Guo,Xi Wang,Yujia Jiang,Kexuan Cheng,Zhixin Yang,T Zheng +11 more
TL;DR: In this article , a humanized neutralizing monoclonal antibody (9-8-h2) was identified to neutralize HAdV55 infection with an IC50 of 0.6050 nM.
Strain specific persistence in the murine lung of Aspergillus fumigatus conidia causes an Allergic Broncho-Pulmonary Aspergillosis-like disease phenotype
Jane T. Jones,Ko-Wei Liu,Xi Wang,Caitlin H. Kowalski,Brandon S. Ross,Kathleen A. M. Mills,Kathleen A. M. Mills,Joshua D. Kerkaert,Tobias M. Hohl,Tobias M. Hohl,Lotus A. Lofgren,Jason E. Stajich,Joshua J. Obar,Robert A. Cramer +13 more
TL;DR: Surprisingly, while viable, W72310 showed little to no growth beyond the conidial stage in the lung, indicating that it is possible that A. fumigatus can cause allergic disease in the lungs without any significant hyphal growth.
3