X. Fu
8 Papers
1 Citations
X. Fu is an academic researcher. The author has contributed to research in topics: Chemistry & Medicine. The author has an hindex of 3, co-authored 6 publications.
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Papers
Discovery of novel coumarin-indole derivatives as tubulin polymerization inhibitors with potent anti-gastric cancer activities.
Jian-Ying Song,Yong-Feng Guan,Wen-bo Liu,Chun Song,Xin-Yi Tian,Ting Zhu,X. Fu,Ying-Qiu Qi,Sai-Yang Zhang +8 more
TL;DR: Wang et al. as discussed by the authors designed, synthesized and evaluated as tubulin polymerization inhibitors targeting the colchicine binding site, and showed that compound MY-413 was a promising lead compound for the further investigation as a potential anti-gastric cancer agent.
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A novel aromatic amide derivative SY-65 co-targeted tubulin and histone deacetylase 1 with potent anticancer activity in vitro and in vivo.
Yin-Ru Li,Fang-Fang Liu,Wen-bo Liu,Yi-Fan Zhang,Xin-Yi Tian,X. Fu,Yan Xu,Jian-Ying Song,Sai-Yang Zhang +8 more
TL;DR: Wang et al. as discussed by the authors reported a novel aromatic amide derivative SY-65 co-targeted tubulin and histone deacetylase 1 with potent anticancer activity in vitro and in vivo.
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Discovery of novel N-benzylarylamide-dithiocarbamate based derivatives as dual inhibitors of tubulin polymerization and LSD1 that inhibit gastric cancers.
Xin-Ying Yuan,Chun Song,Xiu-Juan Liu,Xiao Wang,Mei-Qi Jia,Wang Wang,Wen-bo Liu,X. Fu,Cheng-Yun Jin,Jian-Ying Song,Sai-Yang Zhang +10 more
TL;DR: In this paper , N-benzylarylamide-dithiocarbamate based derivatives were designed, synthesized, and their biological activities as anticancer agents were explored.
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Discovery of a novel Coumarin-Dihydroquinoxalone derivative MY-673 as a tubulin polymerization inhibitor capable of inhibiting the ERK pathway with potent anti-gastric cancer activities.
Jian-Ying Song,Shu-Yu Wang,Xiao Wang,Mei-Qi Jia,Xin-Yi Tian,X. Fu,Cheng-Yun Jin,Sai-Yang Zhang +7 more
TL;DR: Wang et al. as discussed by the authors designed and synthesized a new coumarin-dihydroquinoxalone derivative, MY-673, and evaluated its anticancer potency in vitro and in vivo.
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Discovery of novel arylamide derivatives containing piperazine moiety as inhibitors of tubulin polymerisation with potent liver cancer inhibitory activity
Xiaoyi Shi,H. Jiao,Jiakai Zhang,Xin-Yi Tian,Danfeng Guo,Jie Gao,Mei-Qi Jia,Jian-Ying Song,Sai-Yang Zhang,X. Fu,Hongwei Tang +10 more
TL;DR: The promising bioactivities of compound 16f (MY-1121) make the novel arylamide derivatives have the value for further development as tubulin polymerisation inhibitors with potent anticancer activities.
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