Wylie Vale
Salk Institute for Biological Studies
877 Papers
19.7K Citations
Wylie Vale is an academic researcher from Salk Institute for Biological Studies. The author has contributed to research in topics: Receptor & Somatostatin. The author has an hindex of 163, co-authored 876 publications. Previous affiliations of Wylie Vale include Texas Tech University Health Sciences Center & Hammersmith Hospital.
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Papers
The rat melanin-concentrating hormone messenger ribonucleic acid encodes multiple putative neuropeptides coexpressed in the dorsolateral hypothalamus.
TL;DR: The results explain the staining of a discrete population of dorso-lateral hypothalamic neurons by heretofore seemingly unrelated antisera and provide evidence for the production of multiple novel neuropeptides from a common precursor.
Bombesin affects the central nervous system to produce hyperglycemia in rats.
TL;DR: Bombesin induced hyperglycemia may be mediated via adrenomedullary-catecholamine induced changes in insulin and glucagon secretion resulting in enhanced hepatic glucose output.
Chlordiazepoxide attenuates response suppression induced by corticotropin-releasing factor in the conflict test
TL;DR: The hypothesis that CRF produces behavioral effects consistent with “anxiety” or an increased responsiveness to stress is supported.
Patterns of growth hormone-releasing factor and somatostatin secretion into the hypophysial-portal circulation of the rat
Paul M. Plotsky,Wylie Vale +1 more
TL;DR: It appears that each GH secretory episode is initiated by pulsatile secretion of immunoreactive GRF into the portal circulation, which is preceded by or is concurrent with a moderate reduction of inhibitory tone provided by portal immunore active SRIF.
Erratum to “Antagonism of activin by inhibin and inhibin receptors: a functional role for betaglycan-glycan”
TL;DR: Recent advances in understanding inhibin’s mode of action are summarized focusing on the recent identification of betaglycan as an inhibin co-receptor capable of mediating inhibin action.