Diarrhea and patient outcomes in the intensive care unit: Systematic review and meta-analysis.

目的 分析综合重症监护治疗病房(ICU)患者发生腹泻的相关因素,以指导临床制订最佳治疗方案.方法对2001年1月-2002年12月入住山东省聊城市人民医院综合ICU的危重患者共735例进行回顾性分析,结合文献,综合评价ICU内腹泻发生的原因.结果 735例中,入住ICU前无腹泻,入住24 h后发生腹泻者为86例,发生率为11.70%.引起腹泻的原因主要为:不适当肠内营养51例次(占59.30%),肠道感染18例次(占20.93%),滥用广谱抗生素15例次(占17.44%),大量使用胃肠动力药物11例次(占12.79%),与机械通气有关者5例次(占5.81%).而且综合ICU内发生腹泻患者的年龄[平均(57.71±13.40)岁]、急性生理学与慢性健康状况Ⅱ评分[平均(21.51±4.90)分]及住ICU时间[平均(8.0±1.2)d]均明显高于同期入住综合ICU未发生腹泻患者[分别为(51.20±11.31)岁,(12.01±1.20)分和(4.0±1.0)d,P均<0.05],并且发生腹泻的原因不同于普通病房患者引起腹泻的病因.结论综合ICU患者发生腹泻有其特点和原因,应予以高度重视。

Clinical analysis of the factors related to diarrhea in intensive care unit

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Clinical analysis of the factors related to diarrhea in intensive care unit