Woncheol Lee
University of Michigan
12 Papers
5 Citations
Woncheol Lee is an academic researcher from University of Michigan. The author has contributed to research in topics: Superlattice & Cancer. The author has an hindex of 6, co-authored 11 publications. Previous affiliations of Woncheol Lee include Seoul National University.
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Papers
Hydro-Seq enables contamination-free high-throughput single-cell RNA-sequencing for circulating tumor cells
Yu Heng Cheng,Yu Chih Chen,Eric Lin,Riley Brien,Seungwon Jung,Yu-Ting Chen,Woncheol Lee,Zhijian Hao,Saswat Sahoo,Hyun Min Kang,Jason Cong,Monika L. Burness,Sunitha Nagrath,Max S. Wicha,Euisik Yoon +14 more
TL;DR: Hydro-Seq is presented, a contamination-free high-throughput hydrodynamic scRNA-seq barcoding technique for rare CTCs and Transcriptome analysis of these cells provides insights into monitoring target therapeutics and processes underlying tumor metastasis.
Mesenchymal Stem/Stromal Cell Engulfment Reveals Metastatic Advantage in Breast Cancer
Yu Chih Chen,Maria E. Gonzalez,Boris Burman,Xintao Zhao,Talha Anwar,Mai Tran,Natasha Medhora,Ayse B. Hiziroglu,Woncheol Lee,Yu Heng Cheng,Yehyun Choi,Euisik Yoon,Celina G. Kleer +12 more
TL;DR: It is shown that MSC engulfment capacity is associated with BC cell metastatic potential and generates cells with mesenchymal-like, invasion, and stem cell traits, and a microfluidic platform with the potential to predict BC metastasis in clinical samples is provided.
Single-cell RNA-sequencing of migratory breast cancer cells: discovering genes associated with cancer metastasis.
Yu Chih Chen,Saswat Sahoo,Riley Brien,Seungwon Jung,Brock Humphries,Woncheol Lee,Yu Heng Cheng,Zhixiong Zhang,Kathryn E. Luker,Max S. Wicha,Gary D. Luker,Euisik Yoon,Euisik Yoon +12 more
TL;DR: Using a microfluidic device that enriches migratory breast cancer cells with enhanced capacity for tumor formation and metastasis, genes differentially expressed in migratory cells are identified by high-throughput single-cell RNA-sequencing.
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A reference electrode-free electrochemical biosensor for detecting MMP-9 using a concentric electrode device
JaeWoong Lee,Jun Yeon Yun,Woncheol Lee,Seong-Wook Choi,Jaeheung Lim,Hyeri Jeong,Dong-Sik Shin,Young June Park +7 more
TL;DR: In this article, an electrochemical biosensor integrated with a redox reporter labeled peptide for the detection of matrix metalloproteinase-9 (MMP-9) was reported.
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An effective electrical sensing scheme using AC electrothermal flow on a biosensor platform based on a carbon nanotube network
TL;DR: In this article, a simple and efficient electrical sensing scheme that can be used to overcome the "diffusion limit" of affinity-based biosensors by incorporating the structural advantage of a concentric electrode biosensor platform and the microstirring effect of AC electrothermal flow (ACEF).
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