Wolfhardt Freinbichler
Vienna University of Technology
11 Papers
10 Citations
Wolfhardt Freinbichler is an academic researcher from Vienna University of Technology. The author has contributed to research in topics: Hydroxyl radical & Microdialysis. The author has an hindex of 6, co-authored 11 publications. Previous affiliations of Wolfhardt Freinbichler include University of Florence.
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Papers
Highly reactive oxygen species: detection, formation, and possible functions
Wolfhardt Freinbichler,Maria Alessandra Colivicchi,Chiara Stefanini,Loria Bianchi,Chiara Ballini,Bashkim Misini,Peter Weinberger,Wolfgang Linert,Damir Varešlija,Keith F. Tipton,Laura Della Corte +10 more
TL;DR: This review outlines the processes by which hROS may be formed, their damaging potential, and the evidence that they might have signaling functions and particular attention is given to procedures for hR OS detection and quantitation and their applicability to in vivo studies.
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Clinically available iron chelators induce neuroprotection in the 6-OHDA model of Parkinson’s disease after peripheral administration
David T. Dexter,Sarah A. Statton,Charlotte Whitmore,Wolfhardt Freinbichler,Peter Weinberger,Keith F. Tipton,Laura Della Corte,Roberta J. Ward,Roberta J. Ward,Roberta J. Ward,Robert R. Crichton +10 more
TL;DR: The results confirm that the administration of these chelators show therapeutic efficacy and should be considered as therapeutic agents for the treatment of Parkinson’s disease.
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Validation of a robust and sensitive method for detecting hydroxyl radical formation together with evoked neurotransmitter release in brain microdialysis
Wolfhardt Freinbichler,Maria Alessandra Colivicchi,Manuela Fattori,Chiara Ballini,Keith F. Tipton,Wolfgang Linert,Laura Della Corte +6 more
TL;DR: In vitro results in the Fenton system (Fe2+ +‰H2O2) indicate a mechanism whereby TA2− forms a primary complex with Fe2+ followed by an intramolecular hydroxylation accompanied by intramolescular electron transfer.
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Mechanistic aspects of the Fenton reaction under conditions approximated to the extracellular fluid.
TL;DR: The Fenton reaction was investigated, in a medium approximating to that of the extracellular fluid (ECF), by rapid-mixing stopped flow experiments and HPLC analysis using sodium terephthalate (TA(2-)).
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Study of total antioxidant activity of human serum blood in the pathology of alcoholism.
Elena Korotkova,Wolfhardt Freinbichler,Wolfgang Linert,Elena V. Dorozhko,Mariya V. Bukkel,Evgeniy Vladimirovich Plotnikov,Olesya Voronova +6 more
TL;DR: The TAA of serum blood of patients in pathology before and after treatment is lower than that one of healthy people, however, during the process of 10 days of alcoholism treatment the TAA coefficient increases.
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