Wolfgang Kreis
University of Erlangen-Nuremberg
132 Papers
1K Citations
Wolfgang Kreis is an academic researcher from University of Erlangen-Nuremberg. The author has contributed to research in topics: Digitalis lanata & Cardenolide. The author has an hindex of 24, co-authored 129 publications. Previous affiliations of Wolfgang Kreis include University of Tübingen.
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Papers
•Journal Article
The New Semisynthetic Cardenolide Analog 3β-[2-(1-Amantadine)-1-on-ethylamine]-digitoxigenin (AMANTADIG) Efficiently Suppresses Cell Growth in Human Leukemia and Urological Tumor Cell Lines.
Elke Nolte,Anna Sobel,Sven Wach,Heidi Hertlein,Nadja Ebert,Frieder Müller-Uri,Robert K. Slany,Helge Taubert,Bernd Wullich,Wolfgang Kreis +9 more
TL;DR: The new semisynthetic cardenolide analog AMANTADIG appears effective in cell growth inhibition of leukemia and urological tumor cell lines.
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Crystallization and preliminary crystallographic analysis of selenomethionine-labelled progesterone 5β-reductase from Digitalis lanata Ehrh
TL;DR: A first inspection of the MAD-phased electron-density map shows that 5 beta-POR is a Rossmann-type reductase and the quality of the map is such that it is anticipated that a complete atomic model of 5beta-POR will readily be built.
The catalytic mechanism of the 3-ketosteroid isomerase of Digitalis lanata involves an intramolecular proton transfer and the activity is not associated with the 3β-hydroxysteroid dehydrogenase activity
Nadine Meitinger,Jennifer Munkert,Rodrigo Maia de Pádua,José Dias de Souza Filho,Harald Maid,Walter Bauer,Fernão Castro Braga,Wolfgang Kreis +7 more
TL;DR: It was demonstrated that r Dl 3βHSD does not possess 3-ketosteroid isomerase activity and studies indicate that the isomerization catalyzed by the Dl 2 O proceeds without significant isotope exchange between the medium and the steroid.
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The plant cell wall–A potential source for pharmacologically active polysaccharides
TL;DR: In this paper, four main crude polysaccharide fractions, which represented the complete polymeric carbohydrate pool, were isolated by sequential extraction from Digitalis purpurea leaves and further fractionated further by ion exchange and gel permeation chromatography in order to obtain homogenous polysacchide fractions.
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Extracellular polysaccharides produced by suspension-cultured cells from Digitalis lanata.
TL;DR: Extracellular polysaccharides (ECP) were isolated in yields of up to 4 mg/ml from the culture media of suspension-cultured cells from Digitalis lanata Ehrh and analysis of carbohydrate composition and linkage analysis indicated that thispolysaccharide is an acidic arabinogalactan.
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