Wolfgang Kern
Ludwig Maximilian University of Munich
652 Papers
3.9K Citations
Wolfgang Kern is an academic researcher from Ludwig Maximilian University of Munich. The author has contributed to research in topics: Myeloid leukemia & Leukemia. The author has an hindex of 80, co-authored 585 publications. Previous affiliations of Wolfgang Kern include German Cancer Research Center & University of Münster.
Chat about Author
Papers
A comprehensive approach to the diagnosis of MDS after triage by morphology towards cytogenetics and other techniques
Torsten Haferlach,Ulrike Bacher,Wolfgang Kern,Susanne Schnittger,Winfried Gassmann,Claudia Haferlach +5 more
TL;DR: A multimodal approach including cytomorphology, cytogenetics, fluorescence in situ hybridization (FISH), PCR, and MFC is possible to achieve a comprehensive characterization of MDS.
2
Classification of AML by DNA-oligonucleotide microarrays.
TL;DR: The following chapter gives an overview of the method of gene expression profiling of leukemia samples, its laboratory procedure, and how to approach the analysis of the data.
2
RUNX1 Deletions Are a Novel Mechanism of Loss of Function in AML and Are Associated with Adverse Cytogenetics.
Claudia Haferlach,Vera Grossmann,Melanie Zenger,Wolfgang Kern,Torsten Haferlach,Alexander Kohlmann,Susanne Schnittger +6 more
TL;DR: To clarify whether RUNX1 is also affected by partial or complete deletions in AML, 623 AML patients screened for RunX1 deletions (del) by interphase fluorescence in situ hybridization using probes spanning the complete RUNX 1 gene and a variety of different abnormalities were found.
2
The Two Mutation Hot Spots Ser34 and Gln157 in U2AF1 Show Different Occurrence, Correlation and Clinical Features in Myeloid Malignancies: An Analysis of 785 Cases
TL;DR: U2AF1 has been shown to be most frequently mutated in MDS cases, while rarely mutated in AML and MPN patients, and the two mutation hot spots were affected with different frequencies within the myeloid entities.
2
Reproducible Diagnosis of Chronic Lymphocytic Leukemia (CLL) By Flow Cytometry: An European Research Initiative on CLL (ERIC) & European Society for Clinical Cell Analysis (ESCCA) Harmonisation Project
Andy C. Rawstron,Karl-Anton Kreuzer,Asha Soosapilla,Martin Spacek,Peter Gambell,Neil McIver-brown,Katherina Psarra,Maria Arroz,Raffaella Milani,J. De la Serna,M. Teresa Cedena,Ozren Jakšić,Josep F. Nomdedeu,Carol Moreno,Gian Matteo Rigolin,Antonio Cuneo,P. Johansen,Hans Erik Johnsen,Richard Rosenquist,Carsten Utoft Niemann,Wolfgang Kern,David Westerman,Marek Trneny,Stephen P. Mulligan,Peter Hillmen,David Oscier,Michael Hallek,Paolo Ghia,Emili Montserrat +28 more
- 03 Dec 2015
2