Wolfgang Engel
University of Göttingen
280 Papers
4.9K Citations
Wolfgang Engel is an academic researcher from University of Göttingen. The author has contributed to research in topics: Gene & Embryonic stem cell. The author has an hindex of 65, co-authored 280 publications.
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Papers
Evolutionary conservation of a common pattern of activity of nucleolus organizers during spermatogenesis in vertebrates.
TL;DR: The qualitative analysis of the Ag-stainability of the NORs was in very good agreement with the results obtained for mammals: Ag-stained NORs are detectable during the entire meiotic prophase up to the pachytene stage, completely absent in the meiotic metaphases I and II, and again demonstrable in early spermatid nuclei.
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The giant B chromosome of the cyprinid fish Alburnus alburnus harbours a retrotransposon-derived repetitive DNA sequence.
C. G. Ziegler,Dunja K. Lamatsch,Claus Steinlein,Wolfgang Engel,Manfred Schartl,Michael Schmid +5 more
TL;DR: The results suggest that the supernumerary chromosome of A. alburnus is not derived from the normal chromosome complement but has evolved independently.
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Novel mutations in the Atlastin gene (SPG3A) in families with autosomal dominant hereditary spastic paraplegia and evidence for late onset forms of HSP linked to the SPG3A locus
TL;DR: This work analysed 13 SPG4‐negative families for mutations in the SPG3A gene and identified a mutation in 38% of families, two of which are novel and found both in a family with early onset of symptoms and in a late onset family.
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Molecular cloning of preproacrosin and analysis of its expression pattern in spermatogenesis
Ibrahim M. Adham,Uwe Klemm,Wolf-Martin Maier,Sigrid Hoyer-Fender,Sofia Tsaousidou,Wolfgang Engel +5 more
TL;DR: The preproacrosin cDNA contains at the 3' end a 381-bp sequence which codes for an amino acid sequence not yet found in any other serine proteinase super-family and is suggested to be involved in the recognition and binding of the spermatozoa to the zona pellucida of the ovum.
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Organization in vitro of ovarian cells into testicular structures.
TL;DR: Dissociated ovarian cells of newborn rats cultivated in this medium reorganize into testicular structures and it is concluded that H-Y antigen is responsible for this histomorphologic change.
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