Wolfgang Engel
University of Göttingen
280 Papers
4.9K Citations
Wolfgang Engel is an academic researcher from University of Göttingen. The author has contributed to research in topics: Gene & Embryonic stem cell. The author has an hindex of 65, co-authored 280 publications.
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Papers
Interactions between mouse ZP2 glycoprotein and proacrosin; a mechanism for secondary binding of sperm to the zona pellucida during fertilization.
TL;DR: Evidence is presented that mZP2-proacrosin interactions are important for retention of acrosome-reacted sperm on the egg surface during fertilization and safe mimetics of suramin have potential as non-steroidal antifertility agents.
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The lack of protamine 2 (P2) in boar and bull spermatozoa is due to mutations within the P2 gene
TL;DR: The expression of protamine P2 in boar and bull is investigated and it can be shown that also in these species protamine 2 is transcribed and translated on low levels.
Increase in final stages of follicular atresia and premature decay of corpora lutea in Insl3-deficient mice.
TL;DR: Follicular atresia and luteolysis are accelerated in ovaries of InSl3‐deficient mice probably because of increased apoptosis, and the Insl3 function thus appears to rescue endocrine cells from the apoptotic pathway.
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Hspa4l-Deficient Mice Display Increased Incidence of Male Infertility and Hydronephrosis Development
Torsten Held,Ilona Paprotta,Janchiv Khulan,Bernhardt Hemmerlein,Lutz Binder,Stephan Wolf,Stephanie Schubert,Andreas Meinhardt,Wolfgang Engel,Ibrahim M. Adham +9 more
TL;DR: It is shown that Hspa4l is expressed ubiquitously and predominantly in the testis, and a role in osmotolerance is suggested.
Genomic sequences of human protamines whose genes, PRM1 and PRM2, are clustered.
TL;DR: Comparison of the genomic organization of human and mouse protamine genes revealed greater similarities between the two in the 5'-noncoding region, which could reflect regulatory elements for testis- and spermatid-specific gene expression.
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