Wolfgang Enard
Ludwig Maximilian University of Munich
139 Papers
371 Citations
Wolfgang Enard is an academic researcher from Ludwig Maximilian University of Munich. The author has contributed to research in topics: Biology & Gene. The author has an hindex of 44, co-authored 115 publications. Previous affiliations of Wolfgang Enard include Max Planck Society & Loyola Marymount University.
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Papers
Recent evolution of a TET-controlled and DPPA3/STELLA-driven pathway of passive DNA demethylation in mammals
Christopher B. Mulholland,Atsuya Nishiyama,Joel Ryan,Ryohei Nakamura,Merve Yiğit,Ivo M. Glück,Carina Trummer,Weihua Qin,Michael D. Bartoschek,Franziska R. Traube,Edris Parsa,Enes Ugur,Enes Ugur,Miha Modic,Aishwarya Acharya,Paul Stolz,Christoph Ziegenhain,Michael Wierer,Wolfgang Enard,Thomas Carell,Don C. Lamb,Hiroyuki Takeda,Makoto Nakanishi,Sebastian Bultmann,Heinrich Leonhardt +24 more
TL;DR: It is shown that DPPA3 alone is capable of inducing global DNA demethylation in non-mammalian species (Xenopus and medaka) despite their evolutionary divergence from mammals more than 300 million years ago.
A non-invasive method to generate induced pluripotent stem cells from primate urine
Johanna Geuder,Mari Ohnuki,Lucas E. Wange,Aleksandar Janjic,Johannes W. Bagnoli,Stefan C. Müller,Artur Kaul,Wolfgang Enard +7 more
TL;DR: This study introduces a novel and efficient approach to generate iPSCs non-invasively from primate urine, which will allow to extend the zoo of species available for a comparative approach to molecular and cellular phenotypes.
Generation and characterization of three fibroblast-derived Rhesus Macaque induced pluripotent stem cell lines.
Jessica Jocher,Fiona C. Edenhofer,P. Janssen,Stefan Müller,Dana C. Lopez-Parra,Johanna Geuder,Wolfgang Enard +6 more
TL;DR: Skin fibroblasts from a male individual are reprogrammed to generate three induced pluripotent stem cell (iPSC) lines that exhibit the typical ESC-like colony morphology, express common pluripotency markers, and can differentiate into cells of the three germ layers.
Differences in DNA methylation patterns between humans and chimpanzees
TL;DR: It is found that the extent of the change in methylation pattern is much more extensive in the brain than in the other tissues, and of the 15 CpGs that have significantly changed methylation in the brains of humans and chimpanzees, 14 are more methylated in humans than in chimpanzees.
Author response: The Human Cell Atlas
Aviv Regev,Aviv Regev,Aviv Regev,Sarah A. Teichmann,Sarah A. Teichmann,Sarah A. Teichmann,Eric S. Lander,Eric S. Lander,Eric S. Lander,Ido Amit,Christophe Benoist,Ewan Birney,Bernd Bodenmiller,Bernd Bodenmiller,Peter J. Campbell,Peter J. Campbell,Piero Carninci,Menna R. Clatworthy,Hans Clevers,Bart Deplancke,Ian Dunham,James Eberwine,Roland Eils,Roland Eils,Wolfgang Enard,Andrew Farmer,Lars Fugger,Berthold Göttgens,Nir Hacohen,Nir Hacohen,Muzlifah Haniffa,Martin Hemberg,Seung K. Kim,Paul Klenerman,Paul Klenerman,Arnold R. Kriegstein,Ed S. Lein,Sten Linnarsson,Emma Lundberg,Emma Lundberg,Joakim Lundeberg,Partha P. Majumder,John C. Marioni,John C. Marioni,John C. Marioni,Miriam Merad,Musa M. Mhlanga,Martijn C. Nawijn,Mihai G. Netea,Garry P. Nolan,Dana Pe'er,Anthony Phillipakis,Chris P. Ponting,Stephen R. Quake,Wolf Reik,Wolf Reik,Wolf Reik,Orit Rozenblatt-Rosen,Joshua R. Sanes,Rahul Satija,Ton N. Schumacher,Alex K. Shalek,Alex K. Shalek,Alex K. Shalek,Ehud Shapiro,Padmanee Sharma,Jay W. Shin,Oliver Stegle,Michael R. Stratton,Michael J. T. Stubbington,Fabian J. Theis,Matthias Uhlen,Matthias Uhlen,Alexander van Oudenaarden,Allon Wagner,Fiona M. Watt,Jonathan S. Weissman,Barbara J. Wold,Ramnik J. Xavier,Nir Yosef,Nir Yosef,Human Cell Atlas Meeting Participants +81 more