William Su
Icahn School of Medicine at Mount Sinai
17 Papers
2 Citations
William Su is an academic researcher from Icahn School of Medicine at Mount Sinai. The author has contributed to research in topics: Medicine & Cancer. The author has an hindex of 6, co-authored 10 publications.
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Papers
PTEN inhibits PREX2-catalyzed activation of RAC1 to restrain tumor cell invasion.
Sarah M. Mense,Douglas Barrows,Douglas Barrows,Cindy Hodakoski,Nicole Steinbach,Nicole Steinbach,David Schoenfeld,David Schoenfeld,William Su,Benjamin D. Hopkins,Tao Su,Barry Fine,Hanina Hibshoosh,Ramon Parsons +13 more
TL;DR: It is shown that PTEN suppresses cell migration and invasion by blocking PREX2 activity, and PREx2 mutants are likely selected in cancer to escape PTEN-mediated inhibition of invasion.
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Adjuvant radiation for salivary gland malignancies is associated with improved survival: A National Cancer Database analysis
Richard L. Bakst,William Su,Umut Ozbek,Miriam A. Knoll,Brett A. Miles,Vishal Gupta,Ryan Rhome +6 more
TL;DR: Although an overall survival benefit was not seen in low- and intermediate-risk salivary gland cancers, this study could not address impact on local control because of the limitations of the NCDB.
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Adjuvant Radiation Therapy Alone for HPV Related Oropharyngeal Cancers with High Risk Features.
William Su,Jerry Liu,Brett A. Miles,Eric M. Genden,Krzysztof Misiukiewicz,Marshall R. Posner,Vishal Gupta,Richard L. Bakst +7 more
TL;DR: Preliminary evidence is provided suggesting that the omission of concurrent chemotherapy to adjuvant radiotherapy may offer comparative local control rates with a lower toxicity profile in the setting of HPV+ patients with traditional high risk features.
Human Papilloma Virus-positive Oropharyngeal Squamous Cell Carcinoma in the Elderly.
Eesha Dave,William Su,Vishal Gupta,Brett A. Miles,Elizabeth G. Demicco,Theresa Soriano,Richard L. Bakst +6 more
TL;DR: Elderly individuals with HPV+ OPC have favorable overall survival with high treatment tolerability independent of Charlson co-morbidity score, and should be considered for stage-appropriate care with omission of specific therapies based on absolute contraindications and patient preference.
Long‐term outcomes in patients with recurrent human papillomavirus‐positive oropharyngeal cancer after upfront transoral robotic surgery
William Su,Greeshma Rajeev-Kumar,Martin Kang,Marshall R. Posner,Jerry Liu,William H. Westra,Brett A. Miles,Vishal Gupta,Sonam Sharma,Krzysztof Misiukiewicz,Eric M. Genden,Richard L. Bakst +11 more
TL;DR: Disease course following failure of human papillomavirus‐positive oropharyngeal cancers (HPV + OPC) is characterized following failure after transoral robotic surgery (TORS).
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