William P. Dempsey
ETH Zurich
15 Papers
29 Citations
William P. Dempsey is an academic researcher from ETH Zurich. The author has contributed to research in topics: Zebrafish & Second-harmonic imaging microscopy. The author has an hindex of 10, co-authored 14 publications. Previous affiliations of William P. Dempsey include California Institute of Technology & University of Southern California.
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Papers
Surface functionalization of barium titanate SHG nanoprobes for in vivo imaging in zebrafish.
Jelena Culic-Viskota,William P. Dempsey,William P. Dempsey,Scott E. Fraser,Periklis Pantazis +4 more
TL;DR: This work presents a protocol for the preparation and use of a particular SHG nanoprobe label, barium titanate (BT), for in vivo imaging in living zebrafish embryos, and describes cross-linking of BT to a biotin-linked moiety using click chemistry methods and coating of BT with nonreactive poly(ethylene glycol) (PEG).
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Intercellular bridges in vertebrate gastrulation.
TL;DR: It is found that intercellular bridges join a significant fraction of epiblast cells in the zebrafish embryo, reaching several cell diameters in length and spanning across different regions of the developing embryos.
In vivo single-cell labeling by confined primed conversion
William P. Dempsey,William P. Dempsey,Lada Georgieva,Patrick M. Helbling,Ali Yasin Sonay,Thai V. Truong,Michel Haffner,Periklis Pantazis +7 more
TL;DR: This work shows confined primed conversion in living zebrafish and reveals the complex anatomy of individual neurons packed between neighboring cells, in which low-power, dual-wavelength, continuous-wave illumination results in pronounced photoconversion.
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Regional synapse gain and loss accompany memory formation in larval zebrafish
William P. Dempsey,Zhuowei Du,Anna Nadtochiy,Colton Smith,Karl Czajkowski,Andrey Andreev,Drew N. Robson,Jennifer M. Li,Serina Applebaum,Thai V. Truong,Carl Kesselman,Scott E. Fraser,Don B. Arnold +12 more
TL;DR: The results suggest that memory formation due to classical conditioning is associated with reciprocal changes in synapse numbers in the pallium, and this change could account for the robust nature of memory formation from classical conditioning.
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In vivo cell tracking using PhOTO zebrafish.
TL;DR: The irreversible green-to-red photoconversion property of Dendra2 fusions enables noninvasive, specific and high-contrast selection of targeted cells of interest, which greatly simplifies cell tracking and segmentation in time and space.
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