William J. Rutter
University of California, Berkeley
20 Papers
296 Citations
William J. Rutter is an academic researcher from University of California, Berkeley. The author has contributed to research in topics: Gene & Recombinant DNA. The author has an hindex of 8, co-authored 20 publications.
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Papers
Analysis of the regions flanking the human insulin gene and sequence of an Alu family member
TL;DR: The regions around the human insulin gene have been studied by heteroduplex, hybridization and sequence analysis and indicated that there is a region of heterogeneous length located approximately 700 bp before the 5' end of the gene.
150
Patent
Method for producing recombinant bacterial plasmids containing the coding sequences of higher organisms
William J. Rutter,Howard M. Goodman,Axel Ullrich,John Shine,John Chirgwin,Raymond Pictet +5 more
- 11 Sep 1981
TL;DR: In this paper, a double-stranded cDNA was synthesized using the messenger RNA as a template, inserting the cDNA into a plasmid and transforming a microorganism with the resultant recombinant plasmids.
76
Patent
DNA Transfer vector and transformed microorganism containing human proinsulin and pre-proinsulin genes
Graeme I. Bell,Raymond Pictet,Howard M. Goodman,William J. Rutter +3 more
- 08 Jun 1982
TL;DR: In this paper, a DNA having a base sequence coding for human proinsulin and pre-proinsulin have been cloned, and novel recombinant DNA transfer vectors containing said cloned DNAs have been constructed.
46
Patent
Recombinant bacterial plasmids containing the coding sequences of insulin genes
William J. Rutter,Raymond Pictet,John Chirgwin,Howard M. Goodman,Axel Ullrich,John Shine +5 more
- 28 Jun 1983
TL;DR: In this paper, the authors describe a process for isolating a specific nucleotide sequence containing genetic information, synthesis of DNA having the specific DNA sequence and transfer of the DNA to a host microorganism, which involves isolation of a selected cell population, extraction of intact mRNA from the cells, purification of intact messenger RNA from the extract and subjection of the purified extract to the action of reverse transcriptase in the presence of the four deoxynucleoside triphosphates needed to synthesize a complementary strand.
19
Patent
Method of obtaining a peptide with desired target property
William J. Rutter,Daniel V. Santi +1 more
- 25 Nov 1992
TL;DR: In this paper, a method to obtain selected individual peptides or families thereof which have a target property and optionally to determine the amino acid sequence of a selected peptide or peptides to permit synthesis in practical quantities is disclosed.
16