William E. Alborn
Eli Lilly and Company
35 Papers
371 Citations
William E. Alborn is an academic researcher from Eli Lilly and Company. The author has contributed to research in topics: Biology & Lipoprotein. The author has an hindex of 23, co-authored 35 publications.
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Papers
Genome of the bacterium Streptococcus pneumoniae strain R6.
JoAnn Hoskins,William E. Alborn,Jeffrey S. Arnold,Larry C. Blaszczak,Stanley Gene Burgett,Bradley S. DeHoff,Shawn T. Estrem,Lori Fritz,Dong-Jing Fu,Wendy Fuller,Chad D. Geringer,Raymond Gilmour,Jennifer S. Glass,Hamid Khoja,Angelika R. Kraft,Robert E. Lagace,Donald J. LeBlanc,Linda N. Lee,Elliot J. Lefkowitz,Jin Lu,Patti Matsushima,Scott M. McAhren,Margaret A. Mchenney,Kevin McLeaster,Christopher W. Mundy,Thalia I. Nicas,Franklin H. Norris,MaryJeanne O'Gara,Robert B. Peery,Gregory T. Robertson,Pamela Kay Rockey,Pei-Ming Sun,Malcolm E. Winkler,Yong Yang,Michelle Young-Bellido,Genshi Zhao,Christopher A. Zook,Richard H. Baltz,S. Richard Jaskunas,Paul Robert Rosteck,Paul L. Skatrud,John I. Glass +41 more
TL;DR: In the analysis of the genome, a large number of new uncharacterized genes predicted to encode proteins that either reside on the surface of the cell or are secreted are identified and there may be new targets for vaccine and antibiotic development.
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The novel apolipoprotein A5 is present in human serum, is associated with VLDL, HDL, and chylomicrons, and circulates at very low concentrations compared with other apolipoproteins.
Peter J. O'Brien,William E. Alborn,John H. Sloan,Maverick Ulmer,Amechand Boodhoo,Michael D. Knierman,Albert E. Schultze,Robert J. Konrad +7 more
TL;DR: These data demonstrate for the first time that ApoA5 is a secreted protein present in human serum and is associated with specific lipoprotein particles, and indicate that the circulating concentration of human Apo A5 is very low compared with other apolipoproteins.
Serum Proprotein Convertase Subtilisin Kexin Type 9 Is Correlated Directly with Serum LDL Cholesterol
William E. Alborn,Guoqing Cao,Holly E. Careskey,Yue-Wei Qian,Danise Rogers Subramaniam,Julian Davies,Elaine M Conner,Robert J. Konrad +7 more
TL;DR: PCSK9 is present in human serum, likely not associated with specific lipoprotein particles, and the circulating concentrations of human PCSK9 are directly correlated with LDL and total cholesterol concentrations.
Genetic and enzymatic basis of hygromycin B resistance in Escherichia coli
TL;DR: A plasmid conferring resistance to the aminocyclitol antibiotic hygromycin B was isolated from Escherichia coli and the presence of the phosphotransferase in E. coli correlates with reduced accumulation of [14C]hygromyzin B.
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Identification and Characterization of a Monofunctional Glycosyltransferase from Staphylococcus aureus
Q. May Wang,Robert B. Peery,Robert B. Johnson,William E. Alborn,Wu-Kuang Yeh,Paul L. Skatrud +5 more
TL;DR: The results suggest that this enzyme is natively present in S. aureus cells and that it may play a role in bacterial cell wall biosynthesis.
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