William D. O. Hamilton
7 Papers
412 Citations
William D. O. Hamilton is an academic researcher. The author has contributed to research in topics: Genetically modified crops & Southern blot. The author has an hindex of 7, co-authored 7 publications.
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Papers
Transgenic potato plants with enhanced resistance to the tomato moth, Lacanobia oleracea: growth room trials
Angharad M. R. Gatehouse,Gillian M. Davison,Christine A. Newell,Andrew Merryweather,William D. O. Hamilton,Elisabeth P. J. Burgess,Robert J.C. Gilbert,John A. Gatehouse +7 more
TL;DR: The hypothesis that GNA has a significant antifeedant effect on insects is supported, and expression of CpTI in transgenic potatoes had similar effects to expression of GNA on total insect biomass and survival, but did not afford protection against insect damage to the plant.
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Approaches to insect resistance using transgenic plants
Angharad M. R. Gatehouse,Ying Shi,Kevin S. Powell,Claire Brough,Vaughan A. Hilder,William D. O. Hamilton,Christine A. Newell,Andrew Merryweather,Donald Boulter,John A. Gatehouse +9 more
TL;DR: Data from bioassays of insects using artificial diets, and with transgenic plants, suggest that the in vitro assay of relative inhibitor effectiveness is consistent with the effects of different inhibitors on insect development and survival in vivo.
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Insect-Resistant Transgenic Plants - Choosing the Gene to Do the Job
Angharad M. R. Gatehouse,Vaughan A. Hilder,Kevin S. Powell,Mengfan Wang,Gillian M. Davison,L. N. Gatehouse,Rachel E. Down,H. S. Edmonds,Donald Boulter,Christine A. Newell,Andrew Merryweather,William D. O. Hamilton,John A. Gatehouse +12 more
TL;DR: The relative ease with which specific antibody-encoding genes can be isolated and expressed in heterologous systems has opened up a vast array of applications of recAb technology.
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Production and purification of active snowdrop lectin in Escherichia coli
Marian Longstaff,Kevin S. Powell,John A. Gatehouse,Romaan J.M. Raemaekers,Christine A. Newell,William D. O. Hamilton +5 more
TL;DR: The toxicity of the recombinant G. nivalis agglutinin towards rice brown planthopper (Nilaparvata lugens) was shown to be similar to that of 'native' G.nivalis Agglut inin when incorporated into an artificial diet, and is thus functionally similar to ' native' snowdrop lectin.
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Cloning and initial characterization of 14 myb -related cDNAs from tomato ( Lycopersicon esculentum cv. Ailsa Craig)
TL;DR: A wide range of expression patterns are revealed which include multiple and single transcripts, some of which show marked tissue specificity, and the DNA-binding domains of two tomato myb clones are compared with myb genes from other plant species and organisms.
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