Wietske C. E. den Hartog
Leiden University Medical Center
5 Papers
62 Citations
Wietske C. E. den Hartog is an academic researcher from Leiden University Medical Center. The author has contributed to research in topics: Diffuse large B-cell lymphoma & Chromosome 7 (human). The author has an hindex of 3, co-authored 4 publications.
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Papers
Pulmonary vein and atrial wall pathology in human total anomalous pulmonary venous connection.
Yvonne L. Douglas,Monique R.M. Jongbloed,Wietske C. E. den Hartog,Margot M. Bartelings,Ad J.J.C. Bogers,Tjark Ebels,Marco C. DeRuiter,Adriana C. Gittenberger-de Groot +7 more
TL;DR: The embryonic posterior heart field may be responsible for the abnormal myocardialization and smooth muscle cell formation in TAPVC and an open connection of the PVs with the morphological LA is necessary to enhance susceptibility to PV stenosis and prevent onset of PV originating arrhythmias
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Frequent mutated B2M, EZH2, IRF8, and TNFRSF14 in primary bone diffuse large B-cell lymphoma reflect a GCB phenotype
Ruben A.L. de Groen,Ronald van Eijk,Stefan Böhringer,Tom van Wezel,Richard Raghoo,Dina Ruano,Patty M. Jansen,Inge H. Briaire-de Bruijn,Fleur A de Groot,Karin Kleiverda,Liane te Boome,Valeska Terpstra,Henriette Levenga,Alina Nicolae,Eduardus F. M. Posthuma,Isabelle Focke-Snieders,Lizan Hardi,Wietske C. E. den Hartog,Lara H Böhmer,Pancras C.W. Hogendoorn,Anke van den Berg,Arjan Diepstra,Marcel Nijland,Pieternella J. Lugtenburg,Marie José Kersten,Steven T. Pals,Hendrik Veelken,Judith V.M.G. Bovée,Arjen H.G. Cleven,Joost S.P. Vermaat +29 more
TL;DR: In this article, the authors investigated the genetic background of a large clinically well-annotated cohort of DLBCL with osseous localizations, including primary bone diffuse large B-cell lymphoma (PB-DLBCL) subtypes.
15
Lymphoma-associated paraneoplastic digital ischemia.
F. J. Sherida H. Woei-A-Jin,Jouke T. Tamsma,Laurence V. Khoe,Wietske C. E. den Hartog,Jan J. Gerritsen,Anneke Brand +5 more
TL;DR: This case encompasses the first report of an IgM and C3-mediated thrombotic microangiopathy (TMA) associated with alternative complement pathway activation in a patient with an indolent B cell lymphoma.
14
Polyostotic DLBCL Is Characterized By a NF-Κb Pathway Affecting Molecular Profile and Superior Survival
Ruben A.L. de Groen,Fleur A. de Groot,Lorraine M. de Haan,Tom van Wezel,Troy Noordenbos,Stefan Boehringer,Ronald van Eijk,Richard Raghoo,Dina Ruano,A. Sijs-Szabo,Liane te Boome,Valeska Terpstra,Henriette Levenga,Aline Nicolae,W. Posthuma,Isabelle Focke-Snieders,L. Hardi,Wietske C. E. den Hartog,Lara H Böhmer,A. van den Berg,Pim Mutseaers,M. W. M. van der Poel,Myrurgia Abdul Hamid,F. J. Sherida H. Woei-A-Jin,A. Janssens,Thomas Tousseyn,Judith V.M.G. Bovée,Hendrik Veelken,Steven T. Pals,Arjan Diepstra,Marcel Nijland,Marie José Kersten,P. Jansen,Arjen H.G. Cleven,Joost S.P. Vermaat +34 more
TL;DR: In this article , the molecular characteristics of polyostotic diffuse large B-cell lymphoma (DLBCL) were assessed and compared to disseminated-and primary-bone DLBCL using an extensive targeted next-generation sequencing (tNGS) panel.
Genome Haploidisation with Chromosome 7 Retention in Oncocytic Follicular Thyroid Carcinoma
Willem E. Corver,Dina Ruano,Karin Weijers,Wietske C. E. den Hartog,Merlijn P. van Nieuwenhuizen,Noel F C C de Miranda,Ronald van Eijk,Anneke Middeldorp,Ekaterina S. Jordanova,Jan Oosting,Ellen Kapiteijn,Guido C. Hovens,Jan W. A. Smit,Tom van Wezel,Hans Morreau +14 more
TL;DR: It is demonstrated that recurrent FTC-OV is frequently characterised by genome-wide DNA haploidisation, heterozygous retention of chromosome 7, and endoreduplication of a near-haploid genome.