Wiek H. van Gilst
University Medical Center Groningen
358 Papers
4.9K Citations
Wiek H. van Gilst is an academic researcher from University Medical Center Groningen. The author has contributed to research in topics: Heart failure & Medicine. The author has an hindex of 74, co-authored 345 publications. Previous affiliations of Wiek H. van Gilst include Free University of Berlin & Leiden University.
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Papers
Galectin-3, Renal Function, and Clinical Outcomes: Results from the LURIC and 4D Studies
Christiane Drechsler,Graciela E. Delgado,Christoph Wanner,Katja Blouin,Stefan Pilz,Andreas Tomaschitz,Andreas Tomaschitz,Marcus E. Kleber,Alexander Dressel,Christoph Willmes,Vera Krane,Bernhard K. Krämer,Winfried März,Winfried März,Eberhard Ritz,Wiek H. van Gilst,Pim van der Harst,Rudolf A. de Boer +17 more
TL;DR: Galectin-3 concentrations increased with progressive renal impairment and independently associated with cardiovascular end points, infections, and all-cause death in patients with impaired renal function.
Activation of liver X receptor-alpha reduces activation of the renal and cardiac renin-angiotensin-aldosterone system.
Irma Kuipers,Pim van der Harst,Folkert Kuipers,Linda van Genne,Maaike Goris,Jukka Y. A. Lehtonen,Dirk J. van Veldhuisen,Wiek H. van Gilst,Rudolf A. de Boer +8 more
TL;DR: To determine whether long-term LXR-α activation affects activation of the renal and cardiac renin–angiotensin–aldosterone system (RAAS), mice were treated with T0901317 (T09, a specific synthetic LXR agonist) in combination with the RAAS inducer isoproterenol (ISO).
The relevance of tissue angiotensin-converting enzyme: Manifestations in mechanistic and endpoint data
Victor J. Dzau,Kenneth E. Bernstein,David S. Celermajer,Jerome D. Cohen,Jerome D. Cohen,Björn Dahlöf,John Deanfield,Javier Diez,Helmut Drexler,Roberto Ferrari,Wiek H. van Gilst,Lennart Hansson,Burkhard Hornig,Ahsan Husain,Colin I. Johnston,Harold L. Lazar,Eva Lonn,Thomas F. Lüscher,John Mancini,Albert Mimran,Carl J. Pepine,Ton J. Rabelink,Willem J. Remme,Luis M. Ruilope,Marcel Ruzicka,Heribert Schunkert,Karl Swedberg,Thomas Unger,Douglas E. Vaughan,Michael A. Weber +29 more
TL;DR: Clinical studies comparing the effects of antihypertensives on endothelial function suggest differences and Pharmacokinetic properties of various ACE inhibitors indicate that there are differences in their binding characteristics for tissue ACE.