Wenqing Li
University of California, San Diego
7 Papers
5 Citations
Wenqing Li is an academic researcher from University of California, San Diego. The author has contributed to research in topics: Zebrafish & Intussusceptive angiogenesis. The author has an hindex of 2, co-authored 4 publications. Previous affiliations of Wenqing Li include University of California, Berkeley.
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Papers
Propranolol inhibits cavernous vascular malformations by β1 adrenergic receptor antagonism in animal models
Wenqing Li,Robert Shenkar,Matthew R Detter,Thomas R. Moore,Christian R Benavides,Rhonda Lightle,Romuald Girard,Nicholas Hobson,Ying Cao,Yan Li,Erin Griffin,Carol J. Gallione,Joseph M. Zabramski,Mark H. Ginsberg,Douglas A. Marchuk,Issam A. Awad +15 more
TL;DR: It is reported that propranolol or its S(-) enantiomer dramatically reduced embryonic venous cavernomas in ccm2 mosaic zebrafish, whereas R-(+)-propranolols, lacking β-antagonism, had no effect.
Abortive intussusceptive angiogenesis causes multi-cavernous vascular malformations.
Wenqing Li,Virginia Tran,Iftach Shaked,Belinda Xue,Thomas R. Moore,Rhonda Lightle,David Kleinfeld,Issam A. Awad,Mark H. Ginsberg +8 more
TL;DR: This paper used CRISPR-Cas9 mutagenesis to induce mosaic inactivation of zebrafish ccm2 resulting in a novel lethal multi-cavernous lesion in the embryonic caudal venous plexus (CVP) caused by obstruction of blood flow by intraluminal pillars.
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Kindlin2 enables EphB/ephrinB bi-directional signaling to support vascular development
TL;DR: Kindlin2 has been shown to support EphB4/ephrinB2 bi-directional signaling functions by associating with a highly conserved NIYY motif in the ephrinB2 cytoplasmic tail as mentioned in this paper .
Endothelial struts, a mechanism to generate large lumenized blood vessels de novo
TL;DR: It is shown that endothelial struts facilitate the formation of large blood vessels without being bound by the prerequisite of a cord-like structure, nor are they restricted in size.
Silencing KRIT1 Partially Reverses the Effects of Disturbed Flow on the Endothelial Cell Transcriptome
Amelia Meecham,Sara McCurdy,E. Frias-Anaya,Wenqing Li,Helios Gallego-Gutiérrez,Phu Ngyuen,Julie Li,Shu Chien,John Y.-J. Shyy,Mark H. Ginsberg,Miguel Alejandro Lopez-Ramirez +10 more