Wendy Bollen
Washington University in St. Louis
5 Papers
77 Citations
Wendy Bollen is an academic researcher from Washington University in St. Louis. The author has contributed to research in topics: Salmonella enterica & Salmonella. The author has an hindex of 5, co-authored 5 publications.
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Papers
Regulated programmed lysis of recombinant Salmonella in host tissues to release protective antigens and confer biological containment
Wei Kong,Soo-Young Wanda,Soo-Young Wanda,Xin Zhang,Wendy Bollen,Steven A. Tinge,Kenneth L. Roland,Roy Curtiss,Roy Curtiss +8 more
TL;DR: A biological containment system designed to cause programmed bacterial cell lysis with no survivors is devised and constructed, using Salmonella enterica serovar Typhimurium vaccines for antigen delivery after colonization of host lymphoid tissues.
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Characterization and immunogenicity of Salmonella typhimurium SL1344 and UK-1 delta crp and delta cdt deletion mutants
TL;DR: The results indicate that the attenuation of a highly virulent S. typhimurium strain can yield a vaccine that induces excellent protective immunity to challenge with less-virulentS.
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Protection and immune responses induced by attenuated Salmonella typhimurium UK-1 strains.
TL;DR: S. typhimurium UK-1 Deltacya-12Deltacrp-11 mutant strain chi3985 and its virulence plasmid cured derivative chi4095 are found to be avirulent and able to induce protective immune responses in BALB/c mice.
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Presence of Wild-Type and Attenuated Salmonella enterica Strains in Brain Tissues following Inoculation of Mice by Different Routes
Wendy Bollen,Bronwyn M. Gunn,Bronwyn M. Gunn,Hua Mo,Margarita K. Lay,Roy Curtiss,Roy Curtiss +6 more
TL;DR: The results indicate that i.n. and possibly even oral delivery of live Salmonella vaccines may be unsafe although it is possible to reduce this risk by appropriate genetic modifications.
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Bacteremia Associated with Live Attenuated χ8110 Salmonella enterica serovar Typhi ISP1820 in Healthy Adult Volunteers
TL;DR: The live attenuated chi8110 Salmonella enterica serovar Typhi ISP1820 vaccine was given in a dose-escalation trial to healthy, adult volunteers and only volunteers with bacteremia developed immune responses.
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