Wenbin Wei
10 Papers
Wenbin Wei is an academic researcher. The author has contributed to research in topics: Medicine & Cancer research. The author has co-authored 1 publications.
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Papers
Elevated expression of the RNA-binding protein IGF2BP1 enhances the mRNA stability of INHBA to promote the invasion and migration of esophageal squamous cancer cells
Juanjian Wang,Ding-Xiong Chen,Yu Zhang,Xin Xu,Yan Cai,Wenbin Wei,Jia-Jie Hao,Ming-Rong Wang +7 more
TL;DR: Elevated expression of IGF2BP1 is a frequent event in ESCC tissues and might be a candidate biomarker for the disease, providing a potential therapeutic target for ESCC patients with high expression of the IGF2 BP1.
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Reciprocal inhibition between TP63 and STAT1 regulates anti-tumor immune response through interferon-γ signaling in squamous cancer
Yuan Jiang,Yueyuan Zheng,Yuan-Wei Zhang,Shuai Kong,Jinxiu Dong,Fei Wang,Benjamin Ziman,Sigal Gery,Jia-Jie Hao,Dan Zhou,Jianian Zhou,Allen S Ho,Uttam K Sinha,Jian Chen,Shuo Zhang,Chuntong Yin,Masaharu Hazawa,Zhihao Lu,Wenbin Wei,Mingjie Wang,H. Phillip Koeffler,De-Chen Lin,Yan-Yi Jiang +22 more
TL;DR: This study reveals that TP63 suppresses anti-tumor immune response by inhibiting interferon-γ signaling, and its inhibition enhances CD8+ T cell infiltration and tumor killing in squamous cancer, suggesting a potential biomarker and therapeutic target for immune checkpoint blockade therapy.
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Dysregulation of CXCL14 promotes malignant phenotypes of esophageal squamous carcinoma cells via regulating SRC and EGFR signaling.
Jing Guo,Chen Chang,Li-Yan Yang,Hong-Qing Cai,Dingbang Chen,Yu Zhang,Yan Cai,Juanjuan Wang,Wenbin Wei,Jia-Jie Hao,Ming-Rong Wang +10 more
TL;DR: In this paper , the authors identify abnormal methylation genes implicated in esophageal squamous cell carcinoma (ESCC) using laser-microdissection and whole-genome bisulfite sequencing.
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ANO1 protein as a potential biomarker for esophageal cancer prognosis and precancerous lesion development prediction.
Li Shang,Jia-Jie Hao,Xu Zhao,Jianzhong He,Zhi-Zhou Shi,Hui-Juan Liu,Li-Fei Wu,Yan-Yi Jiang,F. Shi,Yu Zhang,Yi‐Zhen Liu,Tong-Tong Zhang,Xin Xu,Yan Cai,X. Jia,Min Li,Q. Zhan,E. Li,Li-Dong Wang,Wenbin Wei,Ming-Rong Wang +20 more
TL;DR: Positive ANO1 is a promising biomarker to predict the unfavorable outcome for ESCC patients and more importantly, it can predict disease progression of precancerous lesions.
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NEFL promotes invasion and migration of esophageal squamous carcinoma cells via the EGFR/AKT/S6 pathway.
Zhining Fan,Li-Yan Yang,Na Zhang,Dan Feng,Jing Guo,Chen Chang,Qing Yuan,Yan Cai,Yu Zhang,Wenbin Wei,Ming-Rong Wang,Jia-Jie Hao +11 more
- 20 Apr 2022
TL;DR: Data indicate that NEFL overexpression might promote the EMT process of ESCC cells via the EGFR/AKT/S6 pathway, ultimately enhancing the invasion and migration of ES CC cells.
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