Wen Guo Jiang
Cardiff University
659 Papers
6K Citations
Wen Guo Jiang is an academic researcher from Cardiff University. The author has contributed to research in topics: Cancer & Breast cancer. The author has an hindex of 76, co-authored 649 publications. Previous affiliations of Wen Guo Jiang include University of Stirling & Osaka University.
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Papers
•Journal Article
WNT5A expression in human breast cancer
TL;DR: There is a trend for mRNA levels to be lower in cancerous tissue and lower still in those showing more aggressive behaviour, consistent with the hypothesis that Wnt5a is a tumour suppressor gene with potential clinical applications.
The Kiss‑1/Kiss‑1R complex as a negative regulator of cell motility and cancer metastasis (Review)
TL;DR: The Kiss-1 gene has been suggested as a suppressor of metastasis in a various types of cancer, including gastric cancer, oesophageal carcinoma, pancreatic, ovarian, bladder and prostate cancer, through the regulation of cellular migration and invasion.
Vascular endothelial growth inhibitor, expression in human prostate cancer tissue and the impact on adhesion and migration of prostate cancer cells in vitro.
TL;DR: The expression of V EGI is decreased in prostate cancer and is almost absent in tumours with high Gleason scores, which suggests that VEGI functions as a negative regulator for aggressiveness during the development and progression of prostate cancer.
MTSS1: a multifunctional protein and its role in cancer invasion and metastasis
TL;DR: Accumulating evidence for the function of MTSS1 support the concept that it is unlikely to be a metastasis suppressor, but actually acts as a scaffold protein that interacts with multiple partners to regulate actin dynamics.
•Journal Article
Hepatocyte growth factor/scatter factor disrupts epithelial tumour cell-cell adhesion: involvement of beta-catenin.
TL;DR: It is concluded that phosphorylation of beta-catenin by HGF/SF affects its association with E-cadherin at the cell surface and thus regulates E- cadaverin function resulting in colony scattering phenomena.