Weiwei Jin
Beckman Research Institute
6 Papers
8 Citations
Weiwei Jin is an academic researcher from Beckman Research Institute. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 2, co-authored 2 publications. Previous affiliations of Weiwei Jin include City of Hope National Medical Center.
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Papers
Functional deficiency of DNA repair gene EXO5 results in androgen-induced genomic instability and prostate tumorigenesis.
Shafat Ali,Yilan Zhang,Mian Zhou,Hongzhi Li,Weiwei Jin,Li Zheng,Xiaochun Yu,Jeremy M. Stark,Jeffrey N. Weitzel,Binghui Shen +9 more
TL;DR: Genetic and functional validation of the exonuclease 5 mutations indicated that EXO5 is a risk gene for prostate tumorigenesis, likely due to its functions in HDR.
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The Prevalence Rate of Adult Sarcopenic Obesity and Correlation of Appendicular Skeletal Muscle Mass Index with Body Mass Index, Percent Body Fat, Waist-Hip Ratio, Basal Metabolic Rate, and Visceral Fat Area.
Xi Luo,Bin Cai,Weiwei Jin +2 more
TL;DR: In this article , the authors investigated the prevalence rate of adult sarcopenic obesity and discussed its predisposing factors, which is defined as the combination of sarcopenia and obesity diagnosis.
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Identification of genes modified by N6-methyladenosine in patients with colorectal cancer recurrence
Qi-jian Zhu,Xingxing Huang,Shuxian Yu,Lan Shou,Ruonan Zhang,Han Xie,Zimao Liang,Xueni Sun,Jiao Feng,Ting Duan,Mingming Zhang,Yu Xiang,Xinbing Sui,Weiwei Jin,Qibiao Wu +14 more
TL;DR: The m6A modification plays an indispensable role in the formation of TME diversity and complexity, thereby serving as a promising predictive biomarker or therapeutic target for patients with CRC recurrence.
Identification of Genes Related to 5-Fluorouracil Based Chemotherapy for Colorectal Cancer
Xingxing Huang,Kun Ke,Weiwei Jin,Qi-jian Zhu,Qicong Zhu,Ruyi Mei,Ruonan Zhang,Shuxian Yu,Lan Shou,Xueni Sun,Jiao Feng,Ting Duan,Yi-Ping Mou,Tian Xie,Qibiao Wu,Xinbing Sui +15 more
TL;DR: RBP7, as a tumor immune microenvironment (TIME) related gene, was found to have the potential of predicting chemotherapy resistance and poor prognosis of CRC patients and will hopefully be potential prognostic biomarkers to predict chemotherapy resistance for CRC.
hDNA2 nuclease/helicase promotes centromeric DNA replication and genome stability
Zhengke Li,Bochao Liu,Weiwei Jin,Xiwei Wu,Mian Zhou,Vincent Wenzhe Liu,Vincent Wenzhe Liu,Ajay Goel,Zhiyuan Shen,Li Zheng,Binghui Shen +10 more
TL;DR: It is shown that DNA2 binds preferentially to centromeric DNA, and the DNA2 inhibitor C5 mimics DNA2 knockout and synergistically kills cancer cells when combined with an ATR inhibitor, providing mechanistic insights into how DNA2 supports replication of centromic DNA.