Weiping Sun
ShanghaiTech University
5 Papers
12 Citations
Weiping Sun is an academic researcher from ShanghaiTech University. The author has contributed to research in topics: RNA-binding protein & RNA. The author has an hindex of 4, co-authored 5 publications. Previous affiliations of Weiping Sun include Chinese Academy of Sciences.
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Papers
A proximity-tagging system to identify membrane protein–protein interactions
Qiang Liu,Qiang Liu,Jun Zheng,Jun Zheng,Weiping Sun,Weiping Sun,Yinbo Huo,Yinbo Huo,Liye Zhang,Piliang Hao,Haopeng Wang,Min Zhuang +11 more
TL;DR: A proximity-based tagging system, PUP-IT (pupylation-based interaction tagging), to identify membrane protein interactions, and it is demonstrated that this method can identify the interaction between a cell surface receptor and its ligand.
187
Capturing RNA-protein interaction via CRUIS.
Ziheng Zhang,Ziheng Zhang,Weiping Sun,Weiping Sun,Tiezhu Shi,Tiezhu Shi,Pengfei Lu,Min Zhuang,Ji-Long Liu +8 more
TL;DR: A new tool, the CRISPR-based RNA-United Interacting System (CRUIS), which captures RNA–protein interactions in living cells by combining the power ofCRISPR and PUP-IT, a novel proximity targeting system.
70
An activation-induced IL-15 isoform is a natural antagonist for IL-15 function
Lei Zhao,Bo Hu,Yinsheng Zhang,Yuan Song,Dandan Lin,Yonghao Liu,Yu Mei,Yu Mei,Dedy Sandikin,Weiping Sun,Min Zhuang,Haiyan Liu +11 more
TL;DR: IL-15ΔE6 could be induced during immune activation and function as a negative feedback mechanism to dampen IL-15-mediated inflammatory events and reduce the percentages of inflammatory T cells in the spleen and spinal cord.
Identification of a Small Probe That Can Be Conjugated to Proteins by Proximity Labeling.
TL;DR: A novel 14 amino acid peptide substrate is developed for the proximity-labeling enzyme PafA to label antibodies with a biotin tag without affecting the antigen binding capacity of the antibody.
9
A New Method for Studying RNA-binding Proteins on Specific RNAs
Weiping Sun,Ziheng Zhang,Ziheng Zhang,Ji-Long Liu,Min Zhuang +4 more
- 20 May 2021
TL;DR: The CRUIS (CRISPR-based RNA-United Interacting System) as discussed by the authors was proposed to capture RNA-protein interactions in living cells by combining the RNA-binding capacity of CRISPR/Cas13 and the proximity tagging activity of PUP-IT.