Weijun Chen
14 Papers
Weijun Chen is an academic researcher. The author has contributed to research in topics: Medicine & Chemistry. The author has an hindex of 2, co-authored 6 publications.
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Papers
Engineered bacteria combined with doxorubicin nanoparticles suppress angiogenesis and metastasis in murine melanoma models.
Meiyang Yang,Mariana Maciel Conceição,Weijun Chen,Fuwei Yang,Bingke Zhao,Matthew J.A. Wood,Lihua Qiu,Jinghua Chen +7 more
TL;DR: In this article , an engineered bacteria-based system (GDOX@HSEc) was developed using synthetic biology and interfacial chemistry technologies to concurrently produce naturally occurring heparin sulfatase 1 (HSulf-1) inside and anchor doxorubicin-loaded glycogen nanoparticles on the surface.
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Redox-sensitive hyaluronic acid-ferrocene micelles delivering doxorubicin for enhanced tumor treatment by synergistic chemo/chemodynamic therepay
Fuwei Yang,Ping Wei,Meiyang Yang,Weijun Chen,Bingke Zhao,Wenhua Li,Junze Wang,Lihua Qiu,Jinghua Chen +8 more
TL;DR: In this paper , a targeting redox-sensitive micellar system (DOX/FCH) composed of ferrocene (Fc) and hyaluronic acid (HA) was prepared to deliver DOX for synergetic chemotherapy and chemodynamic therapy (CDT).
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Enzyme-loaded glycogen nanoparticles with tumor-targeting Activatable host-guest supramolecule for augmented chemodynamic therapy.
Fuwei Yang,Wenjie Fang,Meiyang Yang,Weijun Chen,Jiamin Xu,Junze Wang,Wen-Hua Li,Bingke Zhao,Lihua Qiu,Jinghua Chen +9 more
TL;DR: In this paper , a new targeted separable [email protected]/HC nanoparticle system was developed to deliver glucose oxidase (GOx) for CDT/starvation tumor therapy.
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Tumor-targeted glycogen nanoparticles loaded with hemin and glucose oxidase to promote tumor synergistic therapy.
Lihua Qiu,Junze Wang,Mariana Maciel Conceição,Shenhuan Liu,Meiyang Yang,Weijun Chen,Miaomiao Long,Matthew J. A. Wood,Jinghua Chen +8 more
TL;DR: In this paper , a novel tumor-targeted glycogen-based nanoparticle system (GN/He/GOx/HA) was developed to co-deliver hemin (He) and GOx, which can self-supply glucose formed upon degradation of glycogen by α-glycosidase in the lysosome environment, in order to achieve synergistic antitumor therapy.
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A Novel CaCu-Metal-Organic-Framework based Multimodal Treatment Platform for Enhanced Synergistic Therapy of Hepatocellular Carcinoma.
Weijun Chen,Meiyang Yang,Huili Wang,Junling Song,Congjin Mei,Lihua Qiu,Jinghua Chen +6 more
TL;DR: A novel CaCu-MOF-based multimodal treatment platform for enhanced synergistic therapy of hepatocellular carcinoma exhibits improved antitumor efficacy through chemotherapy, chemodynamic therapy, calcium overload, and immunotherapy.
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