Weijun Chen
Beijing Institute of Genomics
24 Papers
118 Citations
Weijun Chen is an academic researcher from Beijing Institute of Genomics. The author has contributed to research in topics: Coronavirus & Genome. The author has an hindex of 12, co-authored 24 publications. Previous affiliations of Weijun Chen include Chinese Academy of Sciences & Zhejiang University.
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Papers
Severe acute respiratory syndrome diagnostics using a coronavirus protein microarray
Heng Zhu,Shaohui Hu,Ghil Jona,Xiaowei Zhu,Nate Kreiswirth,Barbara M. Willey,Tony Mazzulli,Guozhen Liu,Guozhen Liu,Qifeng Song,Peng Chen,Mark J. Cameron,Andrea D. Tyler,Jian Wang,Jie Wen,Weijun Chen,Susan R Compton,Michael Snyder +17 more
TL;DR: It is shown that protein microarrays can serve as a rapid, sensitive, and simple tool for large-scale identification of viral-specific antibodies in sera and demonstrated that viral infection can be monitored for many months after infection.
137
Antibody response and viraemia during the course of severe acute respiratory syndrome (SARS)-associated coronavirus infection
Weijun Chen,Zuyuan Xu,Jingsong Mu,Ling Yang,Haixue Gan,Feng Mu,Baoxing Fan,Bo He,Shengyong Huang,Bo You,Yongkui Yang,Xiangjun Tang,Ling Qiu,Yan Qiu,Jie Wen,Jianqiu Fang,Jian Wang +16 more
TL;DR: To understand the time-course of viraemia and antibody responses to severe acute respiratory syndrome-associated coronavirus (SARS-CoV), RT-PCR and ELISA were used to assay 376 blood samples from 135 SARS patients at various stages of the illness, including samples from patients who were in their early convalescent phase.
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The complete genome sequence and proteomics of Yersinia pestis phage Yep-phi.
Xiangna Zhao,Weili Wu,Zhizhen Qi,Yujun Cui,Yanfeng Yan,Zhaobiao Guo,Zuyun Wang,Hu Wang,Haijun Deng,Yan Xue,Weijun Chen,Xiaoyi Wang,Ruifu Yang +12 more
TL;DR: The Yep-phi genome consists of 38 ,616 bp of DNA, including direct terminal repeats of 222 bp, and is predicted to contain 45 ORFs, and most structural proteins were identified by proteomics analysis.
33
A genome sequence of novel SARS-CoV isolates: the genotype, GD-Ins29, leads to a hypothesis of viral transmission in South China.
E-De Qin,Xionglei He,Wei Tian,Wei Tian,Yong Liu,Yong Liu,Wei Li,Wei Li,Jie Wen,Jie Wen,Jingqiang Wang,Jingqiang Wang,Baochang Fan,Qingfa Wu,Qingfa Wu,Guohui Chang,Wuchun Cao,Zuyuan Xu,Zuyuan Xu,Ruifu Yang,Jing Wang,Jing Wang,Man Yu,Yan Li,Yan Li,Jing Xu,Jing Xu,Bingyin Si,Yongwu Hu,Yongwu Hu,Wenming Peng,Lin Tang,Lin Tang,Tao Jiang,Jianping Shi,Jianping Shi,Jia Ji,Jia Ji,Yu Zhang,Yu Zhang,Jia Ye,Jia Ye,Cui’e Wang,Yujun Han,Yujun Han,Jun Zhou,Jun Zhou,Yajun Deng,Yajun Deng,Xiaoyu Li,Jianfei Hu,Jianfei Hu,Caiping Wang,Caiping Wang,Chunxia Yan,Chunxia Yan,Qingrun Zhang,Qingrun Zhang,Jingyue Bao,Jingyue Bao,Guoqing Li,Guoqing Li,Weijun Chen,Weijun Chen,Lin Fang,Lin Fang,Changfeng Li,Changfeng Li,Meng Lei,Meng Lei,Dawei Li,Dawei Li,Wei Tong,Wei Tong,Xiangjun Tian,Xiangjun Tian,Jin Wang,Jin Wang,Bo Zhang,Bo Zhang,Haiqing Zhang,Haiqing Zhang,Yilin Zhang,Yilin Zhang,Hui Zhao,Hui Zhao,Xiaowei Zhang,Xiaowei Zhang,Shuangli Li,Shuangli Li,Xiaojie Cheng,Xiaojie Cheng,Xiuqing Zhang,Xiuqing Zhang,Bin Liu,Bin Liu,Changqing Zeng,Changqing Zeng,Songgang Li,Songgang Li,Xuehai Tan,Xuehai Tan,Siqi Liu,Siqi Liu,Wei Dong,Wei Dong,Jun Wang,Jun Wang,Gane Ka-Shu Wong,Gane Ka-Shu Wong,Jun Yu,Jun Yu,Jian Wang,Jian Wang,Qingyu Zhu,Huanming Yang,Huanming Yang +116 more
TL;DR: A complete genomic sequence of rare isolates (minor genotype) of the SARS-CoV from SARS patients in Guangdong, China, provides a new avenue for the exploration of the virus-host interaction in viral evolution, host pathogenesis, and vaccine development.
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A sensitive and practical method to detect the T790M mutation in the epidermal growth factor receptor
Jing Zhao,Hua‑Hua Feng,Jin‑Yin Zhao,Li‑Cheng Liu,Fei‑Fei Xie,Yan Xu,Min Jiang Chen,Wei Zhong,Long‑Yun Li,Han‑Ping Wang,Li Zhang,Yi Xiao,Weijun Chen,Mengzhao Wang +13 more
TL;DR: Overall, the ACB-ARMS PCR method could be useful for detecting the EGFR T790M mutation in clinical samples that contain only a small number of mutant alleles.