Weihai Ying
7 Papers
2 Citations
Weihai Ying is an academic researcher. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 2, co-authored 5 publications.
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Papers
Phenomic Studies on Diseases: Potential and Challenges
TL;DR: Wang et al. as mentioned in this paper proposed a framework for the regulatory and ethical guidelines for phenomic studies on diseases, and developed effective international cooperation for phenomics-based studies on human diseases.
UV-induced skin’s green autofluorescence is a biomarker for both non-invasive evaluations of the dosages of UV exposures of the skin and non-invasive prediction of UV-induced skin damage
Mingchao Zhang,Weihai Ying +1 more
TL;DR: In this paper , the authors found that UV exposure produced dose-dependent increases in skin green autofluorescence (AF) intensity of mice, which were significantly associated with the UVB dosages.
2
Two-Stage U-Net for Optic Disc/Cup Segmentation
Haibo Yu,Weihai Ying +1 more
- 28 Oct 2022
TL;DR: Wang et al. as discussed by the authors proposed a two-stage U-Net to segment optic disc/cup gradually and achieved pixel-wise AUC of 99.70% and 96.83% for optic disc and cup segmentation separately.
1
A Comprehensive Study of De Novo Mutations on the Protein-Protein Interaction Interfaces Provides New Insights into Developmental Delay
Dhruba Tara Maharjan,Weichen Song,Zhe Liu,Weidi Wang,Wenxiang Cai,Jue Chen,Fei Xu,Weihai Ying,Guan Ning Lin +8 more
TL;DR: In this paper , the authors curated developmental delay datasets from the PsyMuKB database and showed that DD patients showed a higher rate and deleteriousness in DNM missense on the protein-protein interaction (PPI) interface than sibling control.
Journal Article
NAD+ administration profoundly decreases UVC-induced skin damage by attenuating oxidative stress, inflammation, DNA damage and apoptosis.
TL;DR: Wang et al. as discussed by the authors determined the effects of NAD+ on UVC-induced skin damage and investigated the mechanisms underlying the effects, obtaining the following discoveries: First, UVCinduced skin's green autofluorescence (AF) was highly correlated with the extent of UVCindued skin's damage; second, NAD+ administration profoundly decreased UVC induced skin damage; third, NAD + administration significantly attenuated UVC -induced decreases in the levels of mitochondrial superoxide dismutase and catalase; fourth NAD+-induced increase in the level of cyclooxygenase (COX) 2 - a marker of inflammation; fifth, NAD+, administration profoundly attenuated increase in double-strand DNA (dsDNA) damage; and sixth, NAD+.