Wei-Xun Zhou
Peking Union Medical College Hospital
51 Papers
131 Citations
Wei-Xun Zhou is an academic researcher from Peking Union Medical College Hospital. The author has contributed to research in topics: Medicine & Tissue microarray. The author has an hindex of 11, co-authored 38 publications.
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Papers
Single-cell RNA sequencing reveals a pro-invasive cancer-associated fibroblast subgroup associated with poor clinical outcomes in patients with gastric cancer
Xuechun Li,Zhao Sun,Gongxin Peng,Yi-Qin Xiao,Junchao Guo,Bin Wu,Xiaoyi Li,Wei-Xun Zhou,Jiarui Li,Zhe Li,Chunmei Bai,Lin Zhao,Qin Han,Robert Chunhua Zhao,Xiaoyue Wang +14 more
TL;DR: iCAFs and eCAFs not only exhibited enhanced pro-invasive activities but also mobilized the surrounding immune cells to construct a tumor-favorable microenvironment, suggesting that it represents a promising therapeutic strategy for the treatment of GC.
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Expression of LAPTM4B-35: A novel marker of progression, invasiveness and poor prognosis of extrahepatic cholangiocarcinoma☆
TL;DR: It is established that LAPTM4B-35 positively expressed in a great portion of EHCC and might be a novel molecular maker of progression, invasiveness and poor prognosis.
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Overexpression of eukaryotic translation initiation factor 5A2 (EIF5A2) correlates with cell aggressiveness and poor survival in gastric cancer
Qing-Bin Meng,Weiming Kang,Jian-Chun Yu,Yu-Qin Liu,Zhi-Qiang Ma,Li Zhou,Quan-Cai Cui,Wei-Xun Zhou +7 more
TL;DR: Findings indicate that EIF5A2 upregulation plays an important oncogenic role in gastric cancer and may represent a new predictor for poor survival and is a potential therapeutic target for gastriccancer.
Comparison of transmural healing and mucosal healing as predictors of positive long-term outcomes in Crohn's disease.
Li Ma,Wenbo Li,Nan Zhuang,Hong Yang,Wei Liu,Wei-Xun Zhou,Yuxin Jiang,Jianchu Li,Qingli Zhu,Jiaming Qian +9 more
TL;DR: Transmural healing (TH) is being increasingly recognized for reflecting deep remission in Crohn's disease (CD) as mentioned in this paper, but the long-term clinical significance of achieving TH is still not fully kno...
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Expression of c-fos was associated with clinicopathologic characteristics and prognosis in pancreatic cancer.
Junchao Guo,Jian Jian Li,Yupei Zhao,Li-li Zhou,Quan-Cai Cui,Wei-Xun Zhou,Taiping Zhang,Lei You +7 more
TL;DR: High expression of c-fos in cancer tissues was a significant marker of poor overall survival, accompanied by some conventional clinicopathologic variables, such as sex, grade, peri-neural invasion, T and N stages, and cancerous c- fos expression was identified as an independent prognosticator in multivariate analysis.
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