Wei Tang
Chinese Academy of Sciences
934 Papers
1.8K Citations
Wei Tang is an academic researcher from Chinese Academy of Sciences. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 84, co-authored 671 publications. Previous affiliations of Wei Tang include Centre for Life & East China University of Science and Technology.
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Papers
Enhancement of VEGF-Mediated Angiogenesis by 2-N,6-O-Sulfated Chitosan-Coated Hierarchical PLGA Scaffolds.
TL;DR: The fabrication and characterization of 2-N,6-O-sulfated chitosan (26SCS)-coated hierarchical scaffold composed of poly(lactic-co-glycolic acid) (PLGA) microspheres, as a desirable vehicle for vascular endothelial growth factor (VEGF) delivery and consequent angiogenic boosting in vitro is described.
Application of active components from traditional Chinese medicine in treatment of inflammatory bowel disease
TL;DR: The application and the research progress in protecting intestinal epithelial barrier, maintaining intestinal microbial homeostasis, inhibiting causative factors, and regulating Th1/Th17/Treg balance about TCM in the treatment of IBD are summarized.
CRISPR-Cas9-mediated base-editing screening in mice identifies DND1 amino acids that are critical for primordial germ cell development.
Qing Li,Yanjing Li,Suming Yang,Shuo Huang,Meng Yan,Yifu Ding,Wei Tang,Xiwen Lou,Qi Yin,Zhanfei Sun,Lei Lu,Lei Lu,Huijuan Shi,Hongyan Wang,Yong Chen,Jinsong Li,Jinsong Li +16 more
TL;DR: An enhanced third-generation base-editing system with extra nuclear localization sequences that can efficiently introduce a homozygous base mutation in embryonic stem cells is reported and a CRISPR–Cas9-based screen strategy that combines base editing and haploid embryonic stem cell technologies to identify amino acids critical for protein function in mice is developed.
DZ2002 ameliorates fibrosis, inflammation, and vasculopathy in experimental systemic sclerosis models.
Zongwang Zhang,Yanwei Wu,Bing Wu,Qing Qi,Heng Li,Huimin Lu,Chen Fan,Chunlan Feng,Jianping Zuo,Lili Niu,Wei Tang +10 more
TL;DR: Investigations showed that DZ2002 relieved systemic sclerosis by regulating fibrosis TGF-β/Smad signaling pathway and would be a potential drug for the treatment of systemic sclerosis.
LcrQ Coordinates with the YopD-LcrH Complex To Repress lcrF Expression and Control Type III Secretion by Yersinia pseudotuberculosis.
Keke Fei,Huan Yan,Xiaoyan Zeng,Shaojia Huang,Wei Tang,Matthew S. Francis,Shiyun Chen,Yangbo Hu +7 more
TL;DR: In this article, a negative regulatory loop that physically connects LcrQ to the posttranscriptional regulation of LcrF, and this mechanism incorporates RNase E involved in mRNA decay.