Wei Sha
Tongji University
12 Papers
27 Citations
Wei Sha is an academic researcher from Tongji University. The author has contributed to research in topics: Tuberculosis & Medicine. The author has an hindex of 6, co-authored 12 publications.
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Papers
MicroRNA-27a controls the intracellular survival of Mycobacterium tuberculosis by regulating calcium-associated autophagy
Feng Liu,Jianxia Chen,Peng Wang,Haohao Li,Yilong Zhou,Haipeng Liu,Zhonghua Liu,Ruijuan Zheng,Lin Wang,Hua Yang,Zhenling Cui,Fei Wang,Xiaochen Huang,Jie Wang,Wei Sha,Heping Xiao,Baoxue Ge +16 more
TL;DR: It is shown that Mtb-induced MicroRNA-27a targets the ER-associated calcium transporter CACNA2D3, leading to suppression of antimicrobial autophagy and to enhanced intracellular survival of Mtb.
113
Genome-wide association study identifies two risk loci for tuberculosis in Han Chinese
Ruijuan Zheng,Zhiqiang Li,Zhiqiang Li,Fusheng He,Haipeng Liu,Jianhua Chen,Jiayu Chen,Xuefeng Xie,Juan Zhou,Hao Chen,Xiangyang Wu,Juehui Wu,Boyu Chen,Yahui Liu,Haiyan Cui,Lin Fan,Wei Sha,Yin Liu,Jiqiang Wang,Xiaochen Huang,Linfeng Zhang,Feifan Xu,Jie Wang,Yonghong Feng,Lianhua Qin,Hua Yang,Zhonghua Liu,Zhenglin Cui,Feng Liu,Xinchun Chen,Shaorong Gao,Silong Sun,Yongyong Shi,Yongyong Shi,Yongyong Shi,Baoxue Ge +35 more
TL;DR: A three-stage GWAS for TB in Han Chinese populations and find two risk loci near ESRRB and TGM6 and further demonstrate that tgm6 protects mice from Mtb infection is performed, providing new insights into the genetic etiology of TB.
Clinical benefit of delamanid (OPC-67683) in the treatment of multidrug-resistant tuberculosis patients in China.
TL;DR: It was concluded that delamanid was well-tolerated, had low rates of discontinuation, and could be effective for treating MDR-TB.
38
Sensing of mycobacterial arabinogalactan by galectin-9 exacerbates mycobacterial infection.
Xiangyang Wu,Yong Wu,Ruijuan Zheng,Fen Tang,Lianhua Qin,Detian Lai,Lu Zhang,Lingming Chen,Bo Yan,Hua Yang,Yang Wang,Feifei Li,Jinyu Zhang,Fei Wang,Lin Wang,Yajuan Cao,Mingtong Ma,Zhonghua Liu,Jianxia Chen,Xiaochen Huang,Jie Wang,Ruiliang Jin,Peng Wang,Qin Sun,Wei Sha,Liang-Dong Lyu,Pedro Moura-Alves,Pedro Moura-Alves,Anca Dorhoi,Anca Dorhoi,Gang Pei,Peng Zhang,Jiayu Chen,Shaorong Gao,Felix Randow,Gucheng Zeng,Chang Chen,Xin-Shan Ye,Stefan H. E. Kaufmann,Stefan H. E. Kaufmann,Haipeng Liu,Baoxue Ge +41 more
TL;DR: In this paper, the authors reported that mycobacterial arabinogalactan (AG) is recognized by galectin-9 and exacerbates mycobalacterial infection.
23
Sex influences the association between haemostasis and the extent of lung lesions in tuberculosis
Wenling Tan,Adiilah K. Soodeen-Lalloo,Yue Chu,Weijie Xu,Fengfang Chen,Fengfang Chen,Jie Zhang,Wei Sha,Jin Huang,Guanghong Yang,Lianhua Qin,Jie Wang,Xiaochen Huang,Jingyun Shi,Yonghong Feng +14 more
TL;DR: Comparison of the degree of lung injury and clinical indices of well-matched men and women with newly diagnosed TB, and statistical analysis of the correlation between these indices and the extent of lung lesions can provide insights into the mechanism of gender bias in TB.